Deck 20: Drugs Used to Affect Womens Health

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Question
Which food is not considered to be calcium rich?

A)Sardines in oil
B)Cooked turnip greens
C)Firm tofu
D)Raw green beans
E)Canned pink salmon with bones
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Question
What is the best description of premenstrual syndrome (PMS)?

A)The recurrence of physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle
B)The recurrence of severe physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle
C)The recurrence of severe depression 7 to 14 days prior to a menstrual cycle
D)The recurrence of severe abdominal cramping and diarrhea 7 to 14 days prior to a menstrual cycle
Question
In order to be effective,when is the optimal time for administration of the first dose of an estrogen-containing emergency contraception pill?

A)Within 72 hours of intercourse
B)Within 84 hours of intercourse
C)Within 96 hours of intercourse
D)Within 4 days of intercourse
E)Within 1 week of intercourse
Question
Which bone mineral density score confirms a diagnosis of osteoporosis?

A)A score of -2.5 standard deviations or more below the mean for healthy young women
B)A score of -1.5 standard deviations or more below the mean for healthy young women
C)A score of 1.0 standard deviation or more below the mean for healthy young women
D)A score of 2.0 standard deviations or more below the mean for healthy young women
Question
Which class of drugs does not commonly interact with oral contraceptive pills?

A)Penicillins
B)Anticonvulsants
C)Corticosteroids
D)Antifungals
Question
In which condition is vitamin D contraindicated?

A)Hyperthyroidism
B)Parathyroidism
C)Cushing's syndrome
D)Skeletal cancer
Question
Clinicians choosing a contraceptive option must keep in mind the patient's needs.Which question is least relevant in ascertaining the patient's needs?

A)Is the patient breastfeeding?
B)Is the contraceptive intended for long-term use?
C)Does the patient have a family history of pituitary cancer?
D)How quickly does the patient desire fertility to return?
E)Does the patient desire to reduce her frequency of bleeding?
Question
In which patient population is it safest to prescribe oral contraceptives?

A)Those with clotting disorders
B)Those who may be pregnant
C)Those with liver disease
D)Those with undiagnosed vaginal bleeding
E)Those with hypothyroidism
Question
You have prescribed oral bisphosphonates to a patient and are providing instruction on how to avoid dyspepsia.Which instruction should you not include?

A)Take oral bisphosphonates taken with a full glass of water
B)Avoid reclining for a minimum of 30 minutes following the ingestion of oral bisphosphonates
C)Avoid concomitant medication ingestion
D)Take bisphosphonates with food
Question
What accounts for 90% of cases of dysfunctional uterine bleeding (DUB)resulting from unopposed estrogen stimulation in the endometrium?

A)Pregnancy-related condition
B)Trauma
C)Infection
D)Anovulation
E)Endocrinologic disorders
Question
Which option is not an adverse reaction of selective estrogen receptor modulators (SERMs)?

A)Drowsiness
B)Increased risk of venous thromboembolism
C)Hot flashes
D)Leg cramps
E)Hyperactivity
Question
Which of the following is not considered a disadvantage of using of injectable contraceptives?

A)Weight gain
B)Irregular menses
C)Injection site pain
D)Decreased bone density
E)Storage of the injectable contraceptive
Question
In which patient population is transdermal patch contraception not reliable at suppressing ovulation?

A)Patients with hypertension
B)Patients weighing more than 200 lbs
C)Patients with hypopigmentation
D)Patients with polycystic ovary syndrome
Question
Which gender difference does not affect pharmacodynamics and pharmacokinetics in women?

A)Women have longer gastric emptying times,affecting bioavailability and absorption of many oral drugs.
B)Women generally have lower body weights and body mass indexes.
C)Women have higher proportions of body fat.
D)Women have higher proportions of body water.
Question
Which option is not a secondary goal of the medical management of DUB?

A)Prevention of endometrial hyperplasia
B)Treatment of anemia
C)Prevention of future unpredictable bleeding
D)Treatment of underlying endometrial abnormalities
E)Treatment of hormonal disturbances
Question
Which medical conditions are associated with an increased incidence of osteopenia and osteoporosis?

A)Chronic renal disease,cystic fibrosis,and hypothyroidism
B)Cushing's syndrome,diabetes mellitus,and acute renal disease
C)Skeletal cancer,cystic fibrosis,and obesity
D)Hematological disorders,alcoholism,and eating disorders
Question
What is the most common cause of iron deficiency anemia in the developed world?

A)Trauma
B)Menstrual blood loss
C)Lack of dietary intake
D)Decreased folate levels
Question
Which of the following drugs is least likely to increase the incidence of osteoporosis?

A)heparin
B)lithium (Eskalith)
C)cisplatin (Platinol)
D)phenytoin (Dilantin)
E)furosemide (Lasix)
Question
When a patient has a calcium deficiency,a rise in the level of which hormone promotes bone resorption to regain calcium homeostasis?

A)Parathyroid hormone
B)Estrogen
C)Thyroid-stimulating hormone
D)Human gonadotropin hormone
Question
What is the mechanism of action of bisphosphonates?

A)Adhere tightly to bone surfaces and inhibit osteoclastic activity,thereby inhibiting both normal and abnormal bone resorption
B)Encourage osteoblastic activity by enhancing the rapid reproduction of osteoblastic cells,thus increasing the building of new bone
C)Encourage the absorption of calcium and vitamin D,increasing the formation of new bone
D)Interfere with the body's production of vitamin D,decreasing the availability of elemental calcium and osteoblastic activity
Question
Which is a potential dietary interaction with supplemental estrogen?

A)Orange juice may decrease estrogen levels.
B)Cranberry juice may decrease the incidence of urinary tract infections but increase estrogen levels.
C)Pineapple juice may deactivate certain estrogen preparations.
D)Grapefruit juice may increase estrogen levels.
Question
What is one indication for the use of estrogen replacement therapy (ERT)?

A)Prevent conception in women of childbearing age
B)Reduce all symptoms of menopause
C)Prevent bone loss and osteoporosis in all women
D)Treat certain cancers in women
Question
What is the current recommendation of the U.S.Preventative Services Task Force (USPSTF)regarding the use of hormone replacement therapy?

A)The USPSTF recommends the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
B)The USPSTF recommends against the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
C)The USPSTF recommends the routine use of estrogen,but not progestin,for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
D)The USPSTF recommends the routine use of progestin,but not estrogen,the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
Question
Recombinant human parathyroid hormone (PTH)causes bone density to increase by its ability to maintain calcium and phosphorus levels as new bone is formed.In which population is this agent not approved for treatment?

A)Postmenopausal women with severe bone loss
B)Men with osteoporosis who have a high risk of fractures
C)Persons who have not improved on bisphosphonate therapy
D)Perimenopausal women with a family history of osteoporosis
Question
For which patient population must a clinician use caution when prescribing estrogen replacement therapy?

A)Smokers
B)Patients with a history of hyperlipidemia
C)Social alcohol users
D)Patients with a history of gastroesophageal reflux disease
Question
What important patient education point should be discussed with a patient beginning hormone replacement therapy (HRT)?

A)After a missed dose,the patient should double the dose the following day.
B)If over the age of 35,the patient may continue to smoke without increased incidence of adverse effects.
C)The patient may experience increased pigmentation and,therefore,should use sunscreen and wear protective clothing.
D)The patient should have a mammogram every 2 years.
Question
What unique property does calcitonin possess compared with other agents used to treat osteoporosis?

A)It has been shown to decrease the occurrence of vertebral fractures.
B)It has modest analgesic properties in the setting of acute and chronic vertebral compression fractures.
C)It has been shown to be effective in women who are at least 5 years postmenopausal.
D)It has been shown to be effective in the treatment of hyperparathyroidism.
Question
Women between the ages of 15 and 50 are more susceptible to cardiac arrhythmias than men in the same age group.What is the postulated reason for this?

A)The presence of longer QT intervals in women
B)The inotropic effects of estrogen
C)Smaller ventricles in women that are more prone to the effects of ventricular hypertrophy
D)The presence of shorter PR intervals in women
Question
Where is calcitonin produced in humans?

A)Thyroid gland
B)Pancreas
C)Pituitary gland
D)Hypothalamus
Question
Which of the following agents is available as a nasal spray?

A)raloxifene (Evista)
B)alendronate (Fosamax)
C)calcitonin (Miacalcin)
D)parathyroid hormone
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Deck 20: Drugs Used to Affect Womens Health
1
Which food is not considered to be calcium rich?

A)Sardines in oil
B)Cooked turnip greens
C)Firm tofu
D)Raw green beans
E)Canned pink salmon with bones
Raw green beans
2
What is the best description of premenstrual syndrome (PMS)?

A)The recurrence of physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle
B)The recurrence of severe physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle
C)The recurrence of severe depression 7 to 14 days prior to a menstrual cycle
D)The recurrence of severe abdominal cramping and diarrhea 7 to 14 days prior to a menstrual cycle
The recurrence of physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle
3
In order to be effective,when is the optimal time for administration of the first dose of an estrogen-containing emergency contraception pill?

A)Within 72 hours of intercourse
B)Within 84 hours of intercourse
C)Within 96 hours of intercourse
D)Within 4 days of intercourse
E)Within 1 week of intercourse
Within 72 hours of intercourse
4
Which bone mineral density score confirms a diagnosis of osteoporosis?

A)A score of -2.5 standard deviations or more below the mean for healthy young women
B)A score of -1.5 standard deviations or more below the mean for healthy young women
C)A score of 1.0 standard deviation or more below the mean for healthy young women
D)A score of 2.0 standard deviations or more below the mean for healthy young women
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
5
Which class of drugs does not commonly interact with oral contraceptive pills?

A)Penicillins
B)Anticonvulsants
C)Corticosteroids
D)Antifungals
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
6
In which condition is vitamin D contraindicated?

A)Hyperthyroidism
B)Parathyroidism
C)Cushing's syndrome
D)Skeletal cancer
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
7
Clinicians choosing a contraceptive option must keep in mind the patient's needs.Which question is least relevant in ascertaining the patient's needs?

A)Is the patient breastfeeding?
B)Is the contraceptive intended for long-term use?
C)Does the patient have a family history of pituitary cancer?
D)How quickly does the patient desire fertility to return?
E)Does the patient desire to reduce her frequency of bleeding?
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
8
In which patient population is it safest to prescribe oral contraceptives?

A)Those with clotting disorders
B)Those who may be pregnant
C)Those with liver disease
D)Those with undiagnosed vaginal bleeding
E)Those with hypothyroidism
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
9
You have prescribed oral bisphosphonates to a patient and are providing instruction on how to avoid dyspepsia.Which instruction should you not include?

A)Take oral bisphosphonates taken with a full glass of water
B)Avoid reclining for a minimum of 30 minutes following the ingestion of oral bisphosphonates
C)Avoid concomitant medication ingestion
D)Take bisphosphonates with food
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
10
What accounts for 90% of cases of dysfunctional uterine bleeding (DUB)resulting from unopposed estrogen stimulation in the endometrium?

A)Pregnancy-related condition
B)Trauma
C)Infection
D)Anovulation
E)Endocrinologic disorders
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
11
Which option is not an adverse reaction of selective estrogen receptor modulators (SERMs)?

A)Drowsiness
B)Increased risk of venous thromboembolism
C)Hot flashes
D)Leg cramps
E)Hyperactivity
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
12
Which of the following is not considered a disadvantage of using of injectable contraceptives?

A)Weight gain
B)Irregular menses
C)Injection site pain
D)Decreased bone density
E)Storage of the injectable contraceptive
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
13
In which patient population is transdermal patch contraception not reliable at suppressing ovulation?

A)Patients with hypertension
B)Patients weighing more than 200 lbs
C)Patients with hypopigmentation
D)Patients with polycystic ovary syndrome
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
14
Which gender difference does not affect pharmacodynamics and pharmacokinetics in women?

A)Women have longer gastric emptying times,affecting bioavailability and absorption of many oral drugs.
B)Women generally have lower body weights and body mass indexes.
C)Women have higher proportions of body fat.
D)Women have higher proportions of body water.
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
15
Which option is not a secondary goal of the medical management of DUB?

A)Prevention of endometrial hyperplasia
B)Treatment of anemia
C)Prevention of future unpredictable bleeding
D)Treatment of underlying endometrial abnormalities
E)Treatment of hormonal disturbances
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
16
Which medical conditions are associated with an increased incidence of osteopenia and osteoporosis?

A)Chronic renal disease,cystic fibrosis,and hypothyroidism
B)Cushing's syndrome,diabetes mellitus,and acute renal disease
C)Skeletal cancer,cystic fibrosis,and obesity
D)Hematological disorders,alcoholism,and eating disorders
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
17
What is the most common cause of iron deficiency anemia in the developed world?

A)Trauma
B)Menstrual blood loss
C)Lack of dietary intake
D)Decreased folate levels
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
18
Which of the following drugs is least likely to increase the incidence of osteoporosis?

A)heparin
B)lithium (Eskalith)
C)cisplatin (Platinol)
D)phenytoin (Dilantin)
E)furosemide (Lasix)
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
19
When a patient has a calcium deficiency,a rise in the level of which hormone promotes bone resorption to regain calcium homeostasis?

A)Parathyroid hormone
B)Estrogen
C)Thyroid-stimulating hormone
D)Human gonadotropin hormone
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
20
What is the mechanism of action of bisphosphonates?

A)Adhere tightly to bone surfaces and inhibit osteoclastic activity,thereby inhibiting both normal and abnormal bone resorption
B)Encourage osteoblastic activity by enhancing the rapid reproduction of osteoblastic cells,thus increasing the building of new bone
C)Encourage the absorption of calcium and vitamin D,increasing the formation of new bone
D)Interfere with the body's production of vitamin D,decreasing the availability of elemental calcium and osteoblastic activity
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
21
Which is a potential dietary interaction with supplemental estrogen?

A)Orange juice may decrease estrogen levels.
B)Cranberry juice may decrease the incidence of urinary tract infections but increase estrogen levels.
C)Pineapple juice may deactivate certain estrogen preparations.
D)Grapefruit juice may increase estrogen levels.
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
22
What is one indication for the use of estrogen replacement therapy (ERT)?

A)Prevent conception in women of childbearing age
B)Reduce all symptoms of menopause
C)Prevent bone loss and osteoporosis in all women
D)Treat certain cancers in women
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
23
What is the current recommendation of the U.S.Preventative Services Task Force (USPSTF)regarding the use of hormone replacement therapy?

A)The USPSTF recommends the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
B)The USPSTF recommends against the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
C)The USPSTF recommends the routine use of estrogen,but not progestin,for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
D)The USPSTF recommends the routine use of progestin,but not estrogen,the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women.
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
24
Recombinant human parathyroid hormone (PTH)causes bone density to increase by its ability to maintain calcium and phosphorus levels as new bone is formed.In which population is this agent not approved for treatment?

A)Postmenopausal women with severe bone loss
B)Men with osteoporosis who have a high risk of fractures
C)Persons who have not improved on bisphosphonate therapy
D)Perimenopausal women with a family history of osteoporosis
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
25
For which patient population must a clinician use caution when prescribing estrogen replacement therapy?

A)Smokers
B)Patients with a history of hyperlipidemia
C)Social alcohol users
D)Patients with a history of gastroesophageal reflux disease
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
26
What important patient education point should be discussed with a patient beginning hormone replacement therapy (HRT)?

A)After a missed dose,the patient should double the dose the following day.
B)If over the age of 35,the patient may continue to smoke without increased incidence of adverse effects.
C)The patient may experience increased pigmentation and,therefore,should use sunscreen and wear protective clothing.
D)The patient should have a mammogram every 2 years.
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
27
What unique property does calcitonin possess compared with other agents used to treat osteoporosis?

A)It has been shown to decrease the occurrence of vertebral fractures.
B)It has modest analgesic properties in the setting of acute and chronic vertebral compression fractures.
C)It has been shown to be effective in women who are at least 5 years postmenopausal.
D)It has been shown to be effective in the treatment of hyperparathyroidism.
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
28
Women between the ages of 15 and 50 are more susceptible to cardiac arrhythmias than men in the same age group.What is the postulated reason for this?

A)The presence of longer QT intervals in women
B)The inotropic effects of estrogen
C)Smaller ventricles in women that are more prone to the effects of ventricular hypertrophy
D)The presence of shorter PR intervals in women
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
29
Where is calcitonin produced in humans?

A)Thyroid gland
B)Pancreas
C)Pituitary gland
D)Hypothalamus
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
30
Which of the following agents is available as a nasal spray?

A)raloxifene (Evista)
B)alendronate (Fosamax)
C)calcitonin (Miacalcin)
D)parathyroid hormone
Unlock Deck
Unlock for access to all 30 flashcards in this deck.
Unlock Deck
k this deck
locked card icon
Unlock Deck
Unlock for access to all 30 flashcards in this deck.