Question 1

When a patient has a calcium deficiency,a rise in the level of which hormone promotes bone resorption to regain calcium homeostasis?

Accepted Answer

A) Parathyroid hormone 
B) Estrogen 
C) Thyroid-stimulating hormone 
D) Human gonadotropin hormone 
A) Parathyroid hormone 
B) Estrogen 
C) Thyroid-stimulating hormone 
D) Human gonadotropin hormone A

Question 2

What is the current recommendation of the U.S.Preventative Services Task Force (USPSTF)regarding the use of hormone replacement therapy?

Accepted Answer

A) The USPSTF recommends the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
B) The USPSTF recommends against the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
C) The USPSTF recommends the routine use of estrogen,but not progestin,for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
D) The USPSTF recommends the routine use of progestin,but not estrogen,the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
A) The USPSTF recommends the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
B) The USPSTF recommends against the routine use of combined estrogen and progestin for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
C) The USPSTF recommends the routine use of estrogen,but not progestin,for the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. 
D) The USPSTF recommends the routine use of progestin,but not estrogen,the prevention of chronic conditions,such as cardiovascular disease,osteoporosis,and dementia,in postmenopausal women. B

Question 3

Recombinant human parathyroid hormone (PTH)causes bone density to increase by its ability to maintain calcium and phosphorus levels as new bone is formed.In which population is this agent not approved for treatment?

Accepted Answer

A) Postmenopausal women with severe bone loss 
B) Men with osteoporosis who have a high risk of fractures 
C) Persons who have not improved on bisphosphonate therapy 
D) Perimenopausal women with a family history of osteoporosis 
A) Postmenopausal women with severe bone loss 
B) Men with osteoporosis who have a high risk of fractures 
C) Persons who have not improved on bisphosphonate therapy 
D) Perimenopausal women with a family history of osteoporosis D

Question 4

Which food is not considered to be calcium rich?

Accepted Answer

A) Sardines in oil 
B) Cooked turnip greens 
C) Firm tofu 
D) Raw green beans 
E) Canned pink salmon with bones 
A) Sardines in oil 
B) Cooked turnip greens 
C) Firm tofu 
D) Raw green beans 
E) Canned pink salmon with bones

Question 5

Which medical conditions are associated with an increased incidence of osteopenia and osteoporosis?

Accepted Answer

A) Chronic renal disease,cystic fibrosis,and hypothyroidism 
B) Cushing's syndrome,diabetes mellitus,and acute renal disease 
C) Skeletal cancer,cystic fibrosis,and obesity 
D) Hematological disorders,alcoholism,and eating disorders 
A) Chronic renal disease,cystic fibrosis,and hypothyroidism 
B) Cushing's syndrome,diabetes mellitus,and acute renal disease 
C) Skeletal cancer,cystic fibrosis,and obesity 
D) Hematological disorders,alcoholism,and eating disorders

Question 6

What unique property does calcitonin possess compared with other agents used to treat osteoporosis?

Accepted Answer

A) It has been shown to decrease the occurrence of vertebral fractures. 
B) It has modest analgesic properties in the setting of acute and chronic vertebral compression fractures. 
C) It has been shown to be effective in women who are at least 5 years postmenopausal. 
D) It has been shown to be effective in the treatment of hyperparathyroidism. 
A) It has been shown to decrease the occurrence of vertebral fractures. 
B) It has modest analgesic properties in the setting of acute and chronic vertebral compression fractures. 
C) It has been shown to be effective in women who are at least 5 years postmenopausal. 
D) It has been shown to be effective in the treatment of hyperparathyroidism.

Question 7

What is the best description of premenstrual syndrome (PMS)?

Accepted Answer

A) The recurrence of physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle 
B) The recurrence of severe physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle 
C) The recurrence of severe depression 7 to 14 days prior to a menstrual cycle 
D) The recurrence of severe abdominal cramping and diarrhea 7 to 14 days prior to a menstrual cycle 
A) The recurrence of physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle 
B) The recurrence of severe physical and behavioral symptoms 7 to 14 days prior to a menstrual cycle 
C) The recurrence of severe depression 7 to 14 days prior to a menstrual cycle 
D) The recurrence of severe abdominal cramping and diarrhea 7 to 14 days prior to a menstrual cycle

Question 8

Which option is not a secondary goal of the medical management of DUB?

Accepted Answer

A) Prevention of endometrial hyperplasia 
B) Treatment of anemia 
C) Prevention of future unpredictable bleeding 
D) Treatment of underlying endometrial abnormalities 
E) Treatment of hormonal disturbances 
A) Prevention of endometrial hyperplasia 
B) Treatment of anemia 
C) Prevention of future unpredictable bleeding 
D) Treatment of underlying endometrial abnormalities 
E) Treatment of hormonal disturbances

Question 9

Women between the ages of 15 and 50 are more susceptible to cardiac arrhythmias than men in the same age group.What is the postulated reason for this?

Accepted Answer

A) The presence of longer QT intervals in women 
B) The inotropic effects of estrogen 
C) Smaller ventricles in women that are more prone to the effects of ventricular hypertrophy 
D) The presence of shorter PR intervals in women 
A) The presence of longer QT intervals in women 
B) The inotropic effects of estrogen 
C) Smaller ventricles in women that are more prone to the effects of ventricular hypertrophy 
D) The presence of shorter PR intervals in women

Question 10

What is the mechanism of action of bisphosphonates?

Accepted Answer

A) Adhere tightly to bone surfaces and inhibit osteoclastic activity,thereby inhibiting both normal and abnormal bone resorption 
B) Encourage osteoblastic activity by enhancing the rapid reproduction of osteoblastic cells,thus increasing the building of new bone 
C) Encourage the absorption of calcium and vitamin D,increasing the formation of new bone 
D) Interfere with the body's production of vitamin D,decreasing the availability of elemental calcium and osteoblastic activity 
A) Adhere tightly to bone surfaces and inhibit osteoclastic activity,thereby inhibiting both normal and abnormal bone resorption 
B) Encourage osteoblastic activity by enhancing the rapid reproduction of osteoblastic cells,thus increasing the building of new bone 
C) Encourage the absorption of calcium and vitamin D,increasing the formation of new bone 
D) Interfere with the body's production of vitamin D,decreasing the availability of elemental calcium and osteoblastic activity

Question 11

For which patient population must a clinician use caution when prescribing estrogen replacement therapy?

Accepted Answer

A) Smokers 
B) Patients with a history of hyperlipidemia 
C) Social alcohol users 
D) Patients with a history of gastroesophageal reflux disease 
A) Smokers 
B) Patients with a history of hyperlipidemia 
C) Social alcohol users 
D) Patients with a history of gastroesophageal reflux disease

Question 12

In order to be effective,when is the optimal time for administration of the first dose of an estrogen-containing emergency contraception pill?

Accepted Answer

A) Within 72 hours of intercourse 
B) Within 84 hours of intercourse 
C) Within 96 hours of intercourse 
D) Within 4 days of intercourse 
E) Within 1 week of intercourse 
A) Within 72 hours of intercourse 
B) Within 84 hours of intercourse 
C) Within 96 hours of intercourse 
D) Within 4 days of intercourse 
E) Within 1 week of intercourse

Question 13

What important patient education point should be discussed with a patient beginning hormone replacement therapy (HRT)?

Accepted Answer

A) After a missed dose,the patient should double the dose the following day. 
B) If over the age of 35,the patient may continue to smoke without increased incidence of adverse effects. 
C) The patient may experience increased pigmentation and,therefore,should use sunscreen and wear protective clothing. 
D) The patient should have a mammogram every 2 years. 
A) After a missed dose,the patient should double the dose the following day. 
B) If over the age of 35,the patient may continue to smoke without increased incidence of adverse effects. 
C) The patient may experience increased pigmentation and,therefore,should use sunscreen and wear protective clothing. 
D) The patient should have a mammogram every 2 years.

Question 14

In which patient population is it safest to prescribe oral contraceptives?

Accepted Answer

A) Those with clotting disorders 
B) Those who may be pregnant 
C) Those with liver disease 
D) Those with undiagnosed vaginal bleeding 
E) Those with hypothyroidism 
A) Those with clotting disorders 
B) Those who may be pregnant 
C) Those with liver disease 
D) Those with undiagnosed vaginal bleeding 
E) Those with hypothyroidism

Question 15

Which of the following drugs is least likely to increase the incidence of osteoporosis?

Accepted Answer

A) heparin 
B) lithium (Eskalith) 
C) cisplatin (Platinol) 
D) phenytoin (Dilantin) 
E) furosemide (Lasix) 
A) heparin 
B) lithium (Eskalith) 
C) cisplatin (Platinol) 
D) phenytoin (Dilantin) 
E) furosemide (Lasix)

Question 16

Which option is not an adverse reaction of selective estrogen receptor modulators (SERMs)?

Accepted Answer

A) Drowsiness 
B) Increased risk of venous thromboembolism 
C) Hot flashes 
D) Leg cramps 
E) Hyperactivity 
A) Drowsiness 
B) Increased risk of venous thromboembolism 
C) Hot flashes 
D) Leg cramps 
E) Hyperactivity

Question 17

What is one indication for the use of estrogen replacement therapy (ERT)?

Accepted Answer

A) Prevent conception in women of childbearing age 
B) Reduce all symptoms of menopause 
C) Prevent bone loss and osteoporosis in all women 
D) Treat certain cancers in women 
A) Prevent conception in women of childbearing age 
B) Reduce all symptoms of menopause 
C) Prevent bone loss and osteoporosis in all women 
D) Treat certain cancers in women

Question 18

Which bone mineral density score confirms a diagnosis of osteoporosis?

Accepted Answer

A) A score of -2.5 standard deviations or more below the mean for healthy young women 
B) A score of -1.5 standard deviations or more below the mean for healthy young women 
C) A score of 1.0 standard deviation or more below the mean for healthy young women 
D) A score of 2.0 standard deviations or more below the mean for healthy young women 
A) A score of -2.5 standard deviations or more below the mean for healthy young women 
B) A score of -1.5 standard deviations or more below the mean for healthy young women 
C) A score of 1.0 standard deviation or more below the mean for healthy young women 
D) A score of 2.0 standard deviations or more below the mean for healthy young women

Question 19

Which class of drugs does not commonly interact with oral contraceptive pills?

Accepted Answer

A) Penicillins 
B) Anticonvulsants 
C) Corticosteroids 
D) Antifungals 
A) Penicillins 
B) Anticonvulsants 
C) Corticosteroids 
D) Antifungals

Question 20

In which condition is vitamin D contraindicated?

Accepted Answer

A) Hyperthyroidism 
B) Parathyroidism 
C) Cushing's syndrome 
D) Skeletal cancer 
A) Hyperthyroidism 
B) Parathyroidism 
C) Cushing's syndrome 
D) Skeletal cancer

Exam 20: Drugs Used to Affect Womens Health

When a patient has a calcium deficiency,a rise in the level of which hormone promotes bone resorption to regain calcium homeostasis?

What is the current recommendation of the U.S.Preventative Services Task Force (USPSTF)regarding the use of hormone replacement therapy?

Recombinant human parathyroid hormone (PTH)causes bone density to increase by its ability to maintain calcium and phosphorus levels as new bone is formed.In which population is this agent not approved for treatment?

Which food is not considered to be calcium rich?

Which medical conditions are associated with an increased incidence of osteopenia and osteoporosis?

What unique property does calcitonin possess compared with other agents used to treat osteoporosis?

What is the best description of premenstrual syndrome (PMS)?

Which option is not a secondary goal of the medical management of DUB?

Women between the ages of 15 and 50 are more susceptible to cardiac arrhythmias than men in the same age group.What is the postulated reason for this?

What is the mechanism of action of bisphosphonates?

For which patient population must a clinician use caution when prescribing estrogen replacement therapy?

In order to be effective,when is the optimal time for administration of the first dose of an estrogen-containing emergency contraception pill?

What important patient education point should be discussed with a patient beginning hormone replacement therapy (HRT)?

In which patient population is it safest to prescribe oral contraceptives?

Which of the following drugs is least likely to increase the incidence of osteoporosis?

Which option is not an adverse reaction of selective estrogen receptor modulators (SERMs)?

What is one indication for the use of estrogen replacement therapy (ERT)?

Which bone mineral density score confirms a diagnosis of osteoporosis?

Which class of drugs does not commonly interact with oral contraceptive pills?

In which condition is vitamin D contraindicated?

Conscientious and Rational Prescribing in the 21st Century

An Introduction to Pharmacodynamics and Pharmacokinetics

Communicating With Patients About Medications: a Patient-Centered Approach

Drugs Used in the Treatment of Bone and Joint Disorders

Drugs Used in the Treatment of Eye and Ear Disorders

Drugs Used in the Treatment of Cardiovascular Disorders

Drugs Used to Regulate Blood Pressure

Drugs Used in the Treatment of Hyperlipidemias

Drugs Used in the Treatment of Blood Disorders

Drugs Used in the Treatment of Pulmonary Diseases and Disorders

Drugs Used in the Treatment of Common Disorders of the Gastrointestinal System

Drugs Used to Treat Endocrine Gland Disorders

Drugs Used in the Treatment of Diabetes Mellitus

Drugs Used to Treat Common Neurological Conditions

Practical Pharmacotherapy of Drugs Used to Treat Psychiatric Disorders

Drugs Used in the Treatment of Skin Disorders

Modern Approaches to Managing Bacterial Infections

Drugs Used in the Treatment of Nonbacterial Infections

Drugs Used in the Treatment of Neoplasms

Drugs Used to Affect Mens Health

Prescribing for the Geriatric Patient

Prescribing for the Pediatric Patient

Drugs Used to Manage Pain

The Integrative Medicine Pharmacopoeia: Herbals, vitamins, and Dietary Supplements

Agents Used to Manipulate the Immune Response

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