Deck 3: Pharmacodynamics

Question 1

Which of the following drug doses could be described as the most potent?

A)1000 mg per dose
B)800 mg per dose
C)600 mg per dose
D)400 mg per dose

Answer 1

400 mg per dose

Question 2

Which of the following categories would not cause teratogenic effects?

A)Category B
B)Category C
C)Category D
D)Category X

Answer 2

Category B

Question 3

Why would a hypersensitivity to a drug develop?

A)Enzymes in the body overreact to the drug.
B)Tolerance builds as the drug is taken.
C)Antibodies develop after the drug is taken.
D)Drug cannot be eliminated.

Answer 3

Antibodies develop after the drug is taken.

Question 4

Which of the following would be able to occupy a receptor site to prevent the receptor's natural reaction?

A)Antagonist
B)Agonist
C)Inverse antagonist
D)Partial agonist

Question 5

When is efficacy not more important than potency when determining usefulness of drug?

A)Efficacy and potency are not related
B)When side effects are not tolerable
C)When an available dose form is not available
D)When the dose required is too large to administer

Question 6

Which of the following drug doses would be described as the least potent?

A)100 mg per dose
B)80 mg per dose
C)60 mg per dose
D)40 mg per dose

Question 7

When taking the drug digoxin,why must product substitution be carefully considered?

A)A large increase in the dose of the drug administered is needed to produce a greater drug response.
B)The dose required to prolong blood clotting time is near the dose that causes hemorrhage and death.
C)Drugs that have a high efficacy at a low dose are very potent.
D)The drug dose needed to increase the force of heart contractions is similar to the drug dose that can cause the heart to stop beating.

Question 8

Unexpected drug reactions are known as _____ reactions.

A)idiosyncratic
B)adverse
C)idiopathic
D)paroxysmal

Question 9

Which of the following examples could be classified as an idiosyncratic reaction?

A)Dizziness
B)Unexplained rash
C)Nausea
D)Hepatoxicity

Question 10

Repeated exposures to a drug may result in a(n)_____ response to the drug.

A)increased
B)normal
C)decreased
D)adverse

Question 11

The dose-response curve shows the drug's relative _____ and _____.

A)efficacy,strength
B)efficacy,potency
C)potency,mechanism of action
D)sensitivity,efficacy

Question 12

Which of the following measurements for a child would be the most accurate to use to calculate a drug dose?

A)Weight
B)Body surface area
C)Height
D)Weight and age

Question 13

_____ can activate or turn off a receptor and prompt a specific cellular response.

A)Antagonists
B)Agonists
C)Partial antagonists
D)Partial agonists

Question 14

_____ is the ratio of the effective dose to the lethal dose.

A)Dose-response curve
B)Therapeutic index (TI)
C)Maximum dose curve
D)Margin

Question 15

Which of the following populations may need dose adjustments for drugs that are highly lipid soluble?

A)Children
B)Middle-aged men and women
C)Men
D)Women

Question 16

Why would a double-blind study be beneficial in studying the effects of a person's drug response?

A)Strengthens the bias toward the active drug being studied
B)Increases the likelihood that participants will report accurate information
C)Reduces the risk of information being reported based on the placebo effect
D)Increases the chances of participants to receive the active drug during the study

Question 17

Why is naloxone considered a pure antagonist?

A)In the presence of a high concentration,it behaves like a pure antagonist.
B)It binds to an alternative site on the same receptor site as the agonist.
C)It reverses the effect of the receptor by occupying the receptor site and preventing another drug from binding.
D)It has an affinity at the receptor site but produces an opposite action.

Question 18

Which of the following is not a patient-related factor that can increase or decrease a person's response to an administered drug?

A)Chronic disease
B)Drug allergies
C)Obesity
D)Seasonal allergies

Question 19

Which of the following could help improve patient adherence to drug therapy?

A)Explaining to the patient that he or she needs to adhere to the prescriber's directions
B)Placing the proper warning labels on the packaged medication bottle
C)Explaining to the patient the benefits of the drug therapy
D)Talking with the pharmacist about an alternative drug that may be more affordable to the patient

Question 20

Which of the following best explains why the drug-receptor theory is often referred to as being similar to a lock and key?

A)When two or more drugs are administered,the receptor site will allow either drug to bind to the receptor despite its affinity to unlock the receptor.
B)An appropriate drug fit will produce the desired response from the drug receptor.
C)Competitive and non-competitive drugs have an equal chance of unlocking the receptor to produce its intended action.
D)The drug with a reduced affinity has an equal opportunity with a drug that has a greater affinity of unlocking the receptor.

Question 21

MATCHING
Match the following terms and causes.
a.Adverse reaction
b.Hepatotoxicity
c.Nephrotoxicity
d.Teratogen
e.Carcinogen
Undesired effect

Question 22

MATCHING
Match the following terms and causes.
a.Adverse reaction
b.Hepatotoxicity
c.Nephrotoxicity
d.Teratogen
e.Carcinogen
Can be caused by ibuprofen

Question 23

MATCHING
Match the following terms and causes.
a.Adverse reaction
b.Hepatotoxicity
c.Nephrotoxicity
d.Teratogen
e.Carcinogen
Brings harm to developing fetus

Question 24

MATCHING
Match the following terms and causes.
a.Adverse reaction
b.Hepatotoxicity
c.Nephrotoxicity
d.Teratogen
e.Carcinogen
Stimulates growth of cancer

Question 25

MATCHING
Match the following terms and causes.
a.Adverse reaction
b.Hepatotoxicity
c.Nephrotoxicity
d.Teratogen
e.Carcinogen
Can be caused by isoniazid