Question 1

_____ is the ratio of the effective dose to the lethal dose.

Accepted Answer

A) Dose-response curve 
B) Therapeutic index (TI) 
C) Maximum dose curve 
D) Margin 
A) Dose-response curve 
B) Therapeutic index (TI) 
C) Maximum dose curve 
D) Margin B

Question 2

Which of the following measurements for a child would be the most accurate to use to calculate a drug dose?

Accepted Answer

A) Weight 
B) Body surface area 
C) Height 
D) Weight and age 
A) Weight 
B) Body surface area 
C) Height 
D) Weight and age B

Question 3

Which of the following categories would not cause teratogenic effects?

Accepted Answer

A) Category B 
B) Category C 
C) Category D 
D) Category X 
A) Category B 
B) Category C 
C) Category D 
D) Category X A

Question 4

Unexpected drug reactions are known as _____ reactions.

Accepted Answer

A) idiosyncratic 
B) adverse 
C) idiopathic 
D) paroxysmal 
A) idiosyncratic 
B) adverse 
C) idiopathic 
D) paroxysmal

Question 5

When taking the drug digoxin,why must product substitution be carefully considered?

Accepted Answer

A) A large increase in the dose of the drug administered is needed to produce a greater drug response. 
B) The dose required to prolong blood clotting time is near the dose that causes hemorrhage and death. 
C) Drugs that have a high efficacy at a low dose are very potent. 
D) The drug dose needed to increase the force of heart contractions is similar to the drug dose that can cause the heart to stop beating. 
A) A large increase in the dose of the drug administered is needed to produce a greater drug response. 
B) The dose required to prolong blood clotting time is near the dose that causes hemorrhage and death. 
C) Drugs that have a high efficacy at a low dose are very potent. 
D) The drug dose needed to increase the force of heart contractions is similar to the drug dose that can cause the heart to stop beating.

Question 6

Which of the following examples could be classified as an idiosyncratic reaction?

Accepted Answer

A) Dizziness 
B) Unexplained rash 
C) Nausea 
D) Hepatoxicity 
A) Dizziness 
B) Unexplained rash 
C) Nausea 
D) Hepatoxicity

Question 7

Which of the following could help improve patient adherence to drug therapy?

Accepted Answer

A) Explaining to the patient that he or she needs to adhere to the prescriber's directions 
B) Placing the proper warning labels on the packaged medication bottle 
C) Explaining to the patient the benefits of the drug therapy 
D) Talking with the pharmacist about an alternative drug that may be more affordable to the patient 
A) Explaining to the patient that he or she needs to adhere to the prescriber's directions 
B) Placing the proper warning labels on the packaged medication bottle 
C) Explaining to the patient the benefits of the drug therapy 
D) Talking with the pharmacist about an alternative drug that may be more affordable to the patient

Question 8

Which of the following drug doses would be described as the least potent?

Accepted Answer

A) 100 mg per dose 
B) 80 mg per dose 
C) 60 mg per dose 
D) 40 mg per dose 
A) 100 mg per dose 
B) 80 mg per dose 
C) 60 mg per dose 
D) 40 mg per dose

Question 9

_____ can activate or turn off a receptor and prompt a specific cellular response.

Accepted Answer

A) Antagonists 
B) Agonists 
C) Partial antagonists 
D) Partial agonists 
A) Antagonists 
B) Agonists 
C) Partial antagonists 
D) Partial agonists

Question 10

Which of the following is not a patient-related factor that can increase or decrease a person's response to an administered drug?

Accepted Answer

A) Chronic disease 
B) Drug allergies 
C) Obesity 
D) Seasonal allergies 
A) Chronic disease 
B) Drug allergies 
C) Obesity 
D) Seasonal allergies

Question 11

MATCHING
Match the following terms and causes.
-Can be caused by ibuprofen

Accepted Answer

A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen 
A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen

Question 12

Which of the following populations may need dose adjustments for drugs that are highly lipid soluble?

Accepted Answer

A) Children 
B) Middle-aged men and women 
C) Men 
D) Women 
A) Children 
B) Middle-aged men and women 
C) Men 
D) Women

Question 13

MATCHING
Match the following terms and causes.
-Brings harm to developing fetus

Accepted Answer

A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen 
A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen

Question 14

The dose-response curve shows the drug's relative _____ and _____.

Accepted Answer

A) efficacy,strength 
B) efficacy,potency 
C) potency,mechanism of action 
D) sensitivity,efficacy 
A) efficacy,strength 
B) efficacy,potency 
C) potency,mechanism of action 
D) sensitivity,efficacy

Question 15

MATCHING
Match the following terms and causes.
-Stimulates growth of cancer

Accepted Answer

A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen 
A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen

Question 16

Why is naloxone considered a pure antagonist?

Accepted Answer

A) In the presence of a high concentration,it behaves like a pure antagonist. 
B) It binds to an alternative site on the same receptor site as the agonist. 
C) It reverses the effect of the receptor by occupying the receptor site and preventing another drug from binding. 
D) It has an affinity at the receptor site but produces an opposite action. 
A) In the presence of a high concentration,it behaves like a pure antagonist. 
B) It binds to an alternative site on the same receptor site as the agonist. 
C) It reverses the effect of the receptor by occupying the receptor site and preventing another drug from binding. 
D) It has an affinity at the receptor site but produces an opposite action.

Question 17

Which of the following best explains why the drug-receptor theory is often referred to as being similar to a lock and key?

Accepted Answer

A) When two or more drugs are administered,the receptor site will allow either drug to bind to the receptor despite its affinity to unlock the receptor. 
B) An appropriate drug fit will produce the desired response from the drug receptor. 
C) Competitive and non-competitive drugs have an equal chance of unlocking the receptor to produce its intended action. 
D) The drug with a reduced affinity has an equal opportunity with a drug that has a greater affinity of unlocking the receptor. 
A) When two or more drugs are administered,the receptor site will allow either drug to bind to the receptor despite its affinity to unlock the receptor. 
B) An appropriate drug fit will produce the desired response from the drug receptor. 
C) Competitive and non-competitive drugs have an equal chance of unlocking the receptor to produce its intended action. 
D) The drug with a reduced affinity has an equal opportunity with a drug that has a greater affinity of unlocking the receptor.

Question 18

Why would a hypersensitivity to a drug develop?

Accepted Answer

A) Enzymes in the body overreact to the drug. 
B) Tolerance builds as the drug is taken. 
C) Antibodies develop after the drug is taken. 
D) Drug cannot be eliminated. 
A) Enzymes in the body overreact to the drug. 
B) Tolerance builds as the drug is taken. 
C) Antibodies develop after the drug is taken. 
D) Drug cannot be eliminated.

Question 19

Which of the following drug doses could be described as the most potent?

Accepted Answer

A) 1000 mg per dose 
B) 800 mg per dose 
C) 600 mg per dose 
D) 400 mg per dose 
A) 1000 mg per dose 
B) 800 mg per dose 
C) 600 mg per dose 
D) 400 mg per dose

Question 20

MATCHING
Match the following terms and causes.
-Undesired effect

Accepted Answer

A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen 
A) Adverse reaction 
B) Hepatotoxicity 
C) Nephrotoxicity 
D) Teratogen 
E) Carcinogen

Exam 3: Pharmacodynamics

_____ is the ratio of the effective dose to the lethal dose.

Which of the following measurements for a child would be the most accurate to use to calculate a drug dose?

Which of the following categories would not cause teratogenic effects?

Unexpected drug reactions are known as _____ reactions.

When taking the drug digoxin,why must product substitution be carefully considered?

Which of the following examples could be classified as an idiosyncratic reaction?

Which of the following could help improve patient adherence to drug therapy?

Which of the following drug doses would be described as the least potent?

_____ can activate or turn off a receptor and prompt a specific cellular response.

Which of the following is not a patient-related factor that can increase or decrease a person's response to an administered drug?

MATCHING Match the following terms and causes. -Can be caused by ibuprofen

Which of the following populations may need dose adjustments for drugs that are highly lipid soluble?

MATCHING Match the following terms and causes. -Brings harm to developing fetus

The dose-response curve shows the drug's relative _____ and _____.

MATCHING Match the following terms and causes. -Stimulates growth of cancer

Why is naloxone considered a pure antagonist?

Which of the following best explains why the drug-receptor theory is often referred to as being similar to a lock and key?

Why would a hypersensitivity to a drug develop?

Which of the following drug doses could be described as the most potent?

MATCHING Match the following terms and causes. -Undesired effect

Fundamentals of Pharmacology

Principles of Pharmacology

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

Treatment of Alzheimers Disease

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

Treatment of Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux, and Peptic Ulcer Disease

Treatment of Irritable Bowel Syndrome, ulcerative Colitis, and Crohns Disease

Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

Treatment of Thyroid Disorders

Treatment of Diabetes Mellitus

Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

Treatment of Viral Infections

Treatment of Cancers

Vaccines, Immunomodulators, and Immunosuppressants

Treatment of Fungal Infections

Treatment of Decubitus Ulcers and Burns

Treatment of Acne

Treatment of Eczema and Psoriasis

Treatment of Lice and Scabies

Filters

The dose-response curve shows the drug's relative _ and _.