Deck 9: Treatment of Seizure Disorders

Question 1

Which of the following will the antiseizure drug pregabalin not treat?

A)Absence seizures
B)Herpes-related nerve pain
C)Partial seizures
D)Tonic-clonic seizures

Answer 1

Absence seizures

Question 2

_____ seizures often begin with a blank stare,then result in disorientation and repetitive actions during the seizure.

A)Grand mal
B)Partial focal
C)Complex focal
D)Petit mal

Answer 2

Complex focal

Question 3

For which of the following drugs has the U.S.Food and Drug Administration (FDA)required product label changes to warn of the serious adverse effect of suicidal ideations?

A)Dilantin (phenytoin)
B)Cerebyx (fosphenytoin)
C)Sabril (vigabatrin)
D)Valium (diazepam)

Answer 3

Dilantin (phenytoin)

Question 4

Which of the following antiseizure medications belongs to the iminostilbenes class?

A)Ethosuximide
B)Tegremazepine
C)Oxcarbazepine
D)Tiagabine

Question 5

Which of the following drug classes can be used for the treatment of absence seizures?

A)Barbiturates
B)Valproates
C)Iminostilbenes
D)g-Aminobutyric acid (GABA)analogues

Question 6

Which of the following is not an advantage of taking fosphenytoin instead of phenytoin?

A)Fosphenytoin has 100% bioavailability.
B)Fosphenytoin is not available orally.
C)Serum concentrations of fosphenytoin are more predictable when given intramuscularly.
D)Fosphenytoin is available in intravenous (IV)and intramuscular (IM)forms.

Question 7

Common side effects for phenytoin and fosphenytoin include all of the following except _____.

A)sedation
B)slowed thinking
C)nausea and vomiting
D)improved memory

Question 8

Phenytoin and fosphenytoin suppress seizure activity by binding to receptors _____.

A)on voltage-dependent sodium channels
B)thereby blocking calcium channels
C)on active potassium channels
D)opening protein channels so drugs can enter

Question 9

Another name for grand mal seizures is _____ seizures.

A)myoclonic
B)absence
C)focal
D)tonic-clonic

Question 10

Which of the following drugs used to treat seizures has 100% bioavailability when taken orally?

A)Valproic acid
B)Carbamazepine
C)Gabapentin
D)Fosphenytoin

Question 11

What was the first drug approved to treat seizures?

A)Diazepam
B)Gabapentin
C)Phenobarbital
D)Phenytoin

Question 12

Which of the following auxiliary labels should be placed on a prescription for gabapentin because of decreased absorption of the drug when taken together?

A)Do not take with grapefruit juice.
B)Do not take with antacids.
C)Do not take with a fatty meal.
D)Do not take with food.

Question 13

Valproates should be used cautiously in people with a history of _____.

A)liver disease
B)seasonal allergies
C)depression
D)bipolar disorder

Question 14

Carbamazepine can be used to treat which of the following types of seizures?

A)Absence seizures
B)Myoclonic seizures
C)Focal seizures
D)Petit mal seizures

Question 15

Signs of an upcoming seizure are important because they indicate _____.

A)the location of abnormal neuronal firing in the cerebrum
B)the location of abnormal neuronal breakdown in the cerebrum
C)symptoms of a more serious brain disorder
D)misfiring of key neuron relay points in the cerebellum

Question 16

Which of the following is an example of an external cause of seizure?

A)Alcohol withdrawal
B)Sudden spike in temperature
C)Birth defect
D)Eclampsia

Question 17

Stroke and heart attack can cause seizures because the brain becomes deprived of _____.

A)blood
B)oxygen
C)blood and oxygen
D)nutrients

Question 18

Explain why the auxiliary label "Protect from light and moisture" should be placed on a prescription for carbamazepine.

A)It is inactivated by moisture.
B)Light makes the drug ineffective.
C)Light causes increased photosensitivity.
D)Potency is decreased when the drug is exposed to moisture.

Question 19

Ethosuximide inhibits T-type voltage-dependent _____ channels.

A)calcium
B)potassium
C)sodium
D)chloride

Question 20

If infants born to mothers taking phenytoin were born with cleft palates,what would the pregnancy category for this drug be?

A)Category B
B)Category C
C)Category D
D)Category X

Question 21

Which of the following drugs is indicated for the treatment of status epilepticus?

A)Clonazepam
B)Diazepam
C)Amobarbital
D)Primidone

Question 22

MATCHING
Match each of the following drugs with its class.
a.Depakene
b.Tegretol
c.Neurontin
d.Zarontin
e.Luminal
Iminostilbene

Question 23

MATCHING
Match each of the following drugs with its class.
a.Depakene
b.Tegretol
c.Neurontin
d.Zarontin
e.Luminal
Barbiturate

Question 24

MATCHING
Match each of the following drugs with its class.
a.Depakene
b.Tegretol
c.Neurontin
d.Zarontin
e.Luminal
Succinimide

Question 25

Which of the following drugs used to treat seizure disorders is not a controlled substance?

A)Topiramate
B)Lacosamide
C)Pregabalin
D)Chlorazepate

Question 26

MATCHING
Match each of the following drugs with its class.
a.Depakene
b.Tegretol
c.Neurontin
d.Zarontin
e.Luminal
GABA analogue

Question 27

MATCHING
Match each of the following drugs with its class.
a.Depakene
b.Tegretol
c.Neurontin
d.Zarontin
e.Luminal
Valproate