Question 1

Ethosuximide inhibits T-type voltage-dependent _____ channels.

Accepted Answer

A) calcium 
B) potassium 
C) sodium 
D) chloride 
A) calcium 
B) potassium 
C) sodium 
D) chloride A

Question 2

Which of the following drugs used to treat seizures has 100% bioavailability when taken orally?

Accepted Answer

A) Valproic acid 
B) Carbamazepine 
C) Gabapentin 
D) Fosphenytoin 
A) Valproic acid 
B) Carbamazepine 
C) Gabapentin 
D) Fosphenytoin A

Question 3

Signs of an upcoming seizure are important because they indicate _____.

Accepted Answer

A) the location of abnormal neuronal firing in the cerebrum 
B) the location of abnormal neuronal breakdown in the cerebrum 
C) symptoms of a more serious brain disorder 
D) misfiring of key neuron relay points in the cerebellum 
A) the location of abnormal neuronal firing in the cerebrum 
B) the location of abnormal neuronal breakdown in the cerebrum 
C) symptoms of a more serious brain disorder 
D) misfiring of key neuron relay points in the cerebellum A

Question 4

Explain why the auxiliary label "Protect from light and moisture" should be placed on a prescription for carbamazepine.

Accepted Answer

A) It is inactivated by moisture. 
B) Light makes the drug ineffective. 
C) Light causes increased photosensitivity. 
D) Potency is decreased when the drug is exposed to moisture. 
A) It is inactivated by moisture. 
B) Light makes the drug ineffective. 
C) Light causes increased photosensitivity. 
D) Potency is decreased when the drug is exposed to moisture.

Question 5

Which of the following drugs is indicated for the treatment of status epilepticus?

Accepted Answer

A) Clonazepam 
B) Diazepam 
C) Amobarbital 
D) Primidone 
A) Clonazepam 
B) Diazepam 
C) Amobarbital 
D) Primidone

Question 6

Which of the following antiseizure medications belongs to the iminostilbenes class?

Accepted Answer

A) Ethosuximide 
B) Tegremazepine 
C) Oxcarbazepine 
D) Tiagabine 
A) Ethosuximide 
B) Tegremazepine 
C) Oxcarbazepine 
D) Tiagabine

Question 7

Which of the following is an example of an external cause of seizure?

Accepted Answer

A) Alcohol withdrawal 
B) Sudden spike in temperature 
C) Birth defect 
D) Eclampsia 
A) Alcohol withdrawal 
B) Sudden spike in temperature 
C) Birth defect 
D) Eclampsia

Question 8

Which of the following drug classes can be used for the treatment of absence seizures?

Accepted Answer

A) Barbiturates 
B) Valproates 
C) Iminostilbenes 
D) g-Aminobutyric acid (GAB
A) analogues 
A) Barbiturates 
B) Valproates 
C) Iminostilbenes 
D) g-Aminobutyric acid (GAB
A) analogues

Question 9

Phenytoin and fosphenytoin suppress seizure activity by binding to receptors _____.

Accepted Answer

A) on voltage-dependent sodium channels 
B) thereby blocking calcium channels 
C) on active potassium channels 
D) opening protein channels so drugs can enter 
A) on voltage-dependent sodium channels 
B) thereby blocking calcium channels 
C) on active potassium channels 
D) opening protein channels so drugs can enter

Question 10

MATCHING
Match each of the following drugs with its class.
-Valproate

Accepted Answer

A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal 
A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal

Question 11

Which of the following will the antiseizure drug pregabalin not treat?

Accepted Answer

A) Absence seizures 
B) Herpes-related nerve pain 
C) Partial seizures 
D) Tonic-clonic seizures 
A) Absence seizures 
B) Herpes-related nerve pain 
C) Partial seizures 
D) Tonic-clonic seizures

Question 12

Which of the following is not an advantage of taking fosphenytoin instead of phenytoin?

Accepted Answer

A) Fosphenytoin has 100% bioavailability. 
B) Fosphenytoin is not available orally. 
C) Serum concentrations of fosphenytoin are more predictable when given intramuscularly. 
D) Fosphenytoin is available in intravenous (IV)and intramuscular (IM)forms. 
A) Fosphenytoin has 100% bioavailability. 
B) Fosphenytoin is not available orally. 
C) Serum concentrations of fosphenytoin are more predictable when given intramuscularly. 
D) Fosphenytoin is available in intravenous (IV)and intramuscular (IM)forms.

Question 13

Carbamazepine can be used to treat which of the following types of seizures?

Accepted Answer

A) Absence seizures 
B) Myoclonic seizures 
C) Focal seizures 
D) Petit mal seizures 
A) Absence seizures 
B) Myoclonic seizures 
C) Focal seizures 
D) Petit mal seizures

Question 14

MATCHING
Match each of the following drugs with its class.
-GABA analogue

Accepted Answer

A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal 
A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal

Question 15

Which of the following drugs used to treat seizure disorders is not a controlled substance?

Accepted Answer

A) Topiramate 
B) Lacosamide 
C) Pregabalin 
D) Chlorazepate 
A) Topiramate 
B) Lacosamide 
C) Pregabalin 
D) Chlorazepate

Question 16

_____ seizures often begin with a blank stare,then result in disorientation and repetitive actions during the seizure.

Accepted Answer

A) Grand mal 
B) Partial focal 
C) Complex focal 
D) Petit mal 
A) Grand mal 
B) Partial focal 
C) Complex focal 
D) Petit mal

Question 17

MATCHING
Match each of the following drugs with its class.
-Barbiturate

Accepted Answer

A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal 
A) Depakene 
B) Tegretol 
C) Neurontin 
D) Zarontin 
E) Luminal

Question 18

For which of the following drugs has the U.S.Food and Drug Administration (FDA)required product label changes to warn of the serious adverse effect of suicidal ideations?

Accepted Answer

A) Dilantin (phenytoin) 
B) Cerebyx (fosphenytoin) 
C) Sabril (vigabatrin) 
D) Valium (diazepam) 
A) Dilantin (phenytoin) 
B) Cerebyx (fosphenytoin) 
C) Sabril (vigabatrin) 
D) Valium (diazepam)

Question 19

Valproates should be used cautiously in people with a history of _____.

Accepted Answer

A) liver disease 
B) seasonal allergies 
C) depression 
D) bipolar disorder 
A) liver disease 
B) seasonal allergies 
C) depression 
D) bipolar disorder

Question 20

What was the first drug approved to treat seizures?

Accepted Answer

A) Diazepam 
B) Gabapentin 
C) Phenobarbital 
D) Phenytoin 
A) Diazepam 
B) Gabapentin 
C) Phenobarbital 
D) Phenytoin

Exam 9: Treatment of Seizure Disorders

Ethosuximide inhibits T-type voltage-dependent _____ channels.

Which of the following drugs used to treat seizures has 100% bioavailability when taken orally?

Signs of an upcoming seizure are important because they indicate _____.

Explain why the auxiliary label "Protect from light and moisture" should be placed on a prescription for carbamazepine.

Which of the following drugs is indicated for the treatment of status epilepticus?

Which of the following antiseizure medications belongs to the iminostilbenes class?

Which of the following is an example of an external cause of seizure?

Which of the following drug classes can be used for the treatment of absence seizures?

Phenytoin and fosphenytoin suppress seizure activity by binding to receptors _____.

MATCHING Match each of the following drugs with its class. -Valproate

Which of the following will the antiseizure drug pregabalin not treat?

Which of the following is not an advantage of taking fosphenytoin instead of phenytoin?

Carbamazepine can be used to treat which of the following types of seizures?

MATCHING Match each of the following drugs with its class. -GABA analogue

Which of the following drugs used to treat seizure disorders is not a controlled substance?

_____ seizures often begin with a blank stare,then result in disorientation and repetitive actions during the seizure.

MATCHING Match each of the following drugs with its class. -Barbiturate

For which of the following drugs has the U.S.Food and Drug Administration (FDA)required product label changes to warn of the serious adverse effect of suicidal ideations?

Valproates should be used cautiously in people with a history of _____.

What was the first drug approved to treat seizures?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Pain and Migraine Headache

Treatment of Alzheimers Disease

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

Treatment of Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux, and Peptic Ulcer Disease

Treatment of Irritable Bowel Syndrome, ulcerative Colitis, and Crohns Disease

Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

Treatment of Thyroid Disorders

Treatment of Diabetes Mellitus

Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

Treatment of Viral Infections

Treatment of Cancers

Vaccines, Immunomodulators, and Immunosuppressants

Treatment of Fungal Infections

Treatment of Decubitus Ulcers and Burns

Treatment of Acne

Treatment of Eczema and Psoriasis

Treatment of Lice and Scabies

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