Question 1

Predict the major product for the following reaction.

Accepted Answer

The answer of Predict the major product for the following...

Question 2

Predict the structure of the product for the following reaction.

Accepted Answer

The answer of Predict the structure of the product for...

Question 3

Which of these is the rate-determining step in the electrophilic aromatic substitution of benzene?

Accepted Answer

A) Formation of an electrophile 
B) Formation of sigma complex. 
C) Loss of proton from sigma complex. 
D) Addition of electrophile & loss of proton 
E) None of these 
A) Formation of an electrophile 
B) Formation of sigma complex. 
C) Loss of proton from sigma complex. 
D) Addition of electrophile & loss of proton 
E) None of these B

Question 4

Provide the structure(s)of the major intermediate product(s)in the following reaction sequence.

Accepted Answer

The answer of Provide the structure(s)of the major intermediate product(s)in...

Question 5

The electrophile in the nitration reaction of benzene is:

Accepted Answer

A) NO2+ 
B) HNO3 
C) NO3+ 
D) H2SO4 
E) NO2 
A) NO2+ 
B) HNO3 
C) NO3+ 
D) H2SO4 
E) NO2

Question 6

Predict the major product for the following reaction.

Accepted Answer

The answer of Predict the major product for the following...

Question 7

Predict the product for the following reaction.

Accepted Answer

The answer of Predict the product for the following reaction....

Question 8

Predict the structure of the major product for the following reaction.

Accepted Answer

The answer of Predict the structure of the major product...

Question 9

Predict the major product for the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 10

Provide a stepwise curved arrow mechanism for the following reaction.

Accepted Answer

The answer of Provide a stepwise curved arrow mechanism for...

Question 11

Predict the product for the following reaction.

Accepted Answer

The answer of Predict the product for the following reaction....

Question 12

The electrophile in the sulfonation reaction of benzene is:

Accepted Answer

A) SO2+ 
B) H2SO4 
C) SO3+ 
D) H2SO3 
E) SO3 
A) SO2+ 
B) H2SO4 
C) SO3+ 
D) H2SO3 
E) SO3

Question 13

Which one of the following compounds would be most reactive toward electrophilic aromatic substitution?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 14

Predict the major product for the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) I & IV 
A) I 
B) II 
C) III 
D) IV 
E) I & IV

Question 15

Predict the major product for the following reaction.

Accepted Answer

The answer of Predict the major product for the following...

Question 16

Predict the structure of the product for the following reaction.

Accepted Answer

The answer of Predict the structure of the product for...

Question 17

Which one of the following reactions is most likely to give a polysubstituted product?

Accepted Answer

A) Friedel-Crafts alkylation 
B) Friedel-Crafts acylation 
C) Nitration 
D) Sulfonation 
E) Halogenation 
A) Friedel-Crafts alkylation 
B) Friedel-Crafts acylation 
C) Nitration 
D) Sulfonation 
E) Halogenation

Question 18

Predict the major product for the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 19

Predict the major product for the following reaction.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) no reaction 
A) I 
B) II 
C) III 
D) IV 
E) no reaction

Question 20

Which one of the following compounds does not undergo Friedel-Crafts reaction?

Accepted Answer

A) Benzene 
B) Chlorobenzene 
C) Nitrobenzene 
D) Toluene 
E) tert-Butylbenzene 
A) Benzene 
B) Chlorobenzene 
C) Nitrobenzene 
D) Toluene 
E) tert-Butylbenzene

Exam 19: Aromatic Substitution Reactions

Predict the major product for the following reaction.

Predict the structure of the product for the following reaction.

Which of these is the rate-determining step in the electrophilic aromatic substitution of benzene?

Provide the structure(s)of the major intermediate product(s)in the following reaction sequence.

The electrophile in the nitration reaction of benzene is:

Predict the major product for the following reaction.

Predict the product for the following reaction.

Predict the structure of the major product for the following reaction.

Predict the major product for the following reaction.

Provide a stepwise curved arrow mechanism for the following reaction.

Predict the product for the following reaction.

The electrophile in the sulfonation reaction of benzene is:

Which one of the following compounds would be most reactive toward electrophilic aromatic substitution?

Predict the major product for the following reaction.

Predict the major product for the following reaction.

Predict the structure of the product for the following reaction.

Which one of the following reactions is most likely to give a polysubstituted product?

Predict the major product for the following reaction.

Predict the major product for the following reaction.

Which one of the following compounds does not undergo Friedel-Crafts reaction?

A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

Molecular Representations

Acids and Bases

Alkanes and Cycloalkanes

Stereoisomerism

Chemical Reactivity and Mechanisms

Substitution Reactions

Alkenes: Structure and Preparation Via Elimination Reactions

Addition Reactions of Alkenes

Alkynes

Radical Reactions

Synthesis

Alcohols and Phenols

Ethers and Epoxides; Thiols and Sulfides

Nuclear Magnetic Resonance Spectroscopy

Infrared Spectroscopy and Mass Spectrometry

Conjugated Pi Systems and Pericyclic Reactions

Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Alpha Carbon Chemistry: Enols and Enolates

Amines

Carbohydrates

Amino Acids, Peptides, and Proteins

Lipids

Synthetic Polymers

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