Exam 21: Substitution Reactions of Carbonyl Compounds at the a Carbon

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Which of the following are enol forms of ethyl acetoacetate drawn below? Which of the following are enol forms of ethyl acetoacetate drawn below?

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Which is the most acidic proton in the following compound? Which is the most acidic proton in the following compound?

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Which is the kinetic enolate of 2-methylcyclohexanone? Which is the kinetic enolate of 2-methylcyclohexanone?

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What is the major product of the following reaction? What is the major product of the following reaction?

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Which of the following compounds is an enol of compound X drawn below? Which of the following compounds is an enol of compound X drawn below?

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Which of the following would undergo racemization under basic conditions? Which of the following would undergo racemization under basic conditions?

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The malonic ester synthesis can be adapted to synthesize a-amino acids by using diethyl acetamidomalonate as the starting material.Select the structure of the amino acid produced by the following synthesis. The malonic ester synthesis can be adapted to synthesize a-amino acids by using diethyl acetamidomalonate as the starting material.Select the structure of the amino acid produced by the following synthesis.

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