Exam 1: Introduction to Biochemistry

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The diffusion of large molecules such as enzymes is significantly slowed by the presence of the cytoskeleton.

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True

Enzymes are protein catalysts that form an intermediate with a substrate that fits into it.

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A spontaneous chemical reaction always has a change.

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B

A peptide bond is formed by the condensation of different functional groups from two amino acids.

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The only reason phages are not considered to be cells is because they do not contain a plasma membrane.

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Under most biological conditions, acid groups and amino groups are fully protonated.

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The endoplasmic reticulum is the major site of RNA synthesis and the site of assembly of ribosomes.

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Lipids aggregate to form bilayers because some lipid molecules are hydrophobic and other lipid molecules are hydrophilic.

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Fermentation in the absence of cells demonstrated that metabolic processes were chemical in nature.

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Thermodynamics and its laws are obeyed by living cells.

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All prokaryotic cells are about 1/10 the size of an average eukaryotic cell or smaller.

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Actin has been shown to be one of the most evolutionarily conserved proteins. It is present in all eukaryotic cells and frequently is the most abundant protein in the cell.

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Functional groups describe one or more portions of organic compounds found in living cells.

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The modified lock-and-key theory of enzyme action proposed by Emil Fischer has been completely replaced by more modern ideas of catalysis.

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Bioinformatics has permitted rapid advances in our understanding of structural macromolecules from living cells.

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All cells have kept the same general patterns of metabolism, a very similar genetic code and the same monomers or residues.

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Molecules from living cells cannot be synthesized outside of living cells.

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Ribosomes on the surface of rough endoplasmic reticulum are the site of ATP synthesis.

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The study of the energy changes during metabolic reactions is called .

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Eukaryotic cells are distinguished from prokaryotes by their usually larger size, a complex cytoskeleton and membrane-bounded organelles.

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