Question 1

Why would the alcohol in the following compound need to be protected before reaction?

Accepted Answer

A) If it isn't protected, the product will be a carboxylic acid. 
B) The Grignard reagent will react with the alcohol before the ketone. 
C) Magnesium is Lewis acidic and will coordinate with the alcohol. 
D) There is no need to protect the alcohol. 
A) If it isn't protected, the product will be a carboxylic acid. 
B) The Grignard reagent will react with the alcohol before the ketone. 
C) Magnesium is Lewis acidic and will coordinate with the alcohol. 
D) There is no need to protect the alcohol. B

Question 2

What will be the product of the following reaction (before any aqueous work-up)?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV C

Question 3

Both LiAlH4 and NaBH4 are reducing agents.Which statement about these reagents is true?

Accepted Answer

A) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is greater than the polarity of the Al-H bond, so LiAlH4 is the stronger reducing agent. 
B) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is greater than the polarity of the Al-H bond, so LiAlH4 is the weaker reducing agent. 
C) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is less than the polarity of the Al-H bond, so LiAlH4 is the stronger reducing agent. 
D) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is less than the polarity of the Al-H bond, so LiAlH4 is the weaker reducing agent. 
A) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is greater than the polarity of the Al-H bond, so LiAlH4 is the stronger reducing agent. 
B) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is greater than the polarity of the Al-H bond, so LiAlH4 is the weaker reducing agent. 
C) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is less than the polarity of the Al-H bond, so LiAlH4 is the stronger reducing agent. 
D) Both reagents contain polar metal-hydrogen bonds.The polarity of the B-H bond is less than the polarity of the Al-H bond, so LiAlH4 is the weaker reducing agent. C

Question 4

Which reagent can be used to reduce the alkene in cyclopentenone?

Accepted Answer

A) NaBH4  
B) LiAlH4  
C) H2 and Pd-C 
D) DIBAL-H 
A) NaBH4  
B) LiAlH4  
C) H2 and Pd-C 
D) DIBAL-H

Question 5

What is the major organic product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 6

What is the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 7

What is the starting material in the reaction below?

Accepted Answer

A) Bromobenzene 
B) Benzyl bromide 
C) Benzoic acid 
D) Lithium benzoate 
A) Bromobenzene 
B) Benzyl bromide 
C) Benzoic acid 
D) Lithium benzoate

Question 8

What is the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 9

What reagent would be used to reduce an amide to an amine?

Accepted Answer

A) NaBH4  
B) LiAlH(OtBu)3  
C) LiAlH4  
D) FeCl3  
A) NaBH4  
B) LiAlH(OtBu)3  
C) LiAlH4  
D) FeCl3

Question 10

Why are ketones less reactive than aldehydes?

Accepted Answer

A) Ketones are more sterically hindered. 
B) Ketones are less electron deficient due to donation from the two alkyl groups. 
C) The statement is false; ketones are more reactive than aldehydes. 
D) Both (a) Ketones are more sterically hindered and (b) Ketones are less electron deficient due to donation from the two alkyl groups. 
A) Ketones are more sterically hindered. 
B) Ketones are less electron deficient due to donation from the two alkyl groups. 
C) The statement is false; ketones are more reactive than aldehydes. 
D) Both (a) Ketones are more sterically hindered and (b) Ketones are less electron deficient due to donation from the two alkyl groups.

Question 11

What is the missing reagent in the reaction below?

Accepted Answer

A) PhMgBr then H2O 
B) Benzene, AlCl3  
C) Ph2CuLi then H2O 
D) PhLi then H2O 
A) PhMgBr then H2O 
B) Benzene, AlCl3  
C) Ph2CuLi then H2O 
D) PhLi then H2O

Question 12

What is the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 13

What is the name of the general reaction type that aldehydes and ketones undergo?

Accepted Answer

A) Electrophilic addition 
B) Nucleophilic addition 
C) Nucleophilic substitution 
D) Electrophilic substitution 
A) Electrophilic addition 
B) Nucleophilic addition 
C) Nucleophilic substitution 
D) Electrophilic substitution

Question 14

What is the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 15

What is the missing reagent in the reaction below?

Accepted Answer

A) [1] LiAlH4, [2] H2O 
B) [1] CH3MgBr (excess), [2] H2O 
C) [1] (CH3)2CuLi (excess), [2] H2O 
D) [1] DIBAL-H, [2] H2O 
A) [1] LiAlH4, [2] H2O 
B) [1] CH3MgBr (excess), [2] H2O 
C) [1] (CH3)2CuLi (excess), [2] H2O 
D) [1] DIBAL-H, [2] H2O

Question 16

What is the missing reagent in the reaction below?

Accepted Answer

A) [1] LiAlH4, [2] H2O 
B) [1] CH2=CHLi, [2] H2O 
C) [1] (CH2=CH)2CuLi, [2] H2O 
D) [1] DIBAL-H, [2] H2O 
A) [1] LiAlH4, [2] H2O 
B) [1] CH2=CHLi, [2] H2O 
C) [1] (CH2=CH)2CuLi, [2] H2O 
D) [1] DIBAL-H, [2] H2O

Question 17

What is the major organic product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 18

What is the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 19

What is the major organic product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 20

A carbonyl group, C=O, and an alkene, C=C, double bonds are both sp2 hybridized.However, the chemistry of These two functional groups is very different.This can be explained by which of the following statements?

Accepted Answer

A) The bond angle of the carbonyl is larger than the bond angle of the alkene. 
B) The electronegative oxygen of the C=O group makes this bond polar. 
C) The bond of the C=C is longer that the bond of the C=O. 
D) There is more steric crowding in the carbonyl than in the alkene. 
A) The bond angle of the carbonyl is larger than the bond angle of the alkene. 
B) The electronegative oxygen of the C=O group makes this bond polar. 
C) The bond of the C=C is longer that the bond of the C=O. 
D) There is more steric crowding in the carbonyl than in the alkene.

Exam 20: Introduction to Carbonyl Chemistry;

Why would the alcohol in the following compound need to be protected before reaction?

What will be the product of the following reaction (before any aqueous work-up)?

Both LiAlH4 and NaBH4 are reducing agents.Which statement about these reagents is true?

Which reagent can be used to reduce the alkene in cyclopentenone?

What is the major organic product of the following reaction?

What is the product of the following reaction?

What is the starting material in the reaction below?

What is the product of the following reaction?

What reagent would be used to reduce an amide to an amine?

Why are ketones less reactive than aldehydes?

What is the missing reagent in the reaction below?

What is the product of the following reaction?

What is the name of the general reaction type that aldehydes and ketones undergo?

What is the product of the following reaction?

What is the missing reagent in the reaction below?

What is the missing reagent in the reaction below?

What is the major organic product of the following reaction?

What is the product of the following reaction?

What is the major organic product of the following reaction?

A carbonyl group, C=O, and an alkene, C=C, double bonds are both sp2 hybridized.However, the chemistry of These two functional groups is very different.This can be explained by which of the following statements?

Structure and Bonding

Acids and Bases

Introduction to Organic Molecules and Functional Groups

Alkanes

Stereochemistry

Understanding Organic Reactions

Alkyl Halides and Nucleophilic Substitution

Alkyl Halides and Elimination Reactions

Alcohols, Ethers, and Related Compounds

Alkenes

Alkynes

Oxidation and Reduction

Mass Spectrometry and Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Radical Reactions

Conjugation, Resonance, and Dienes

Benzene and Aromatic Compounds

Reactions of Aromatic Compounds

Carboxylic Acids and the Acidity of the O-H Bond

Aldehydes and Ketones Nucleophilic Addition

Carboxylic Acids and Derivatives

Substitution Reactions of Carbonyl Compounds at the Alpha-Carbon

Carbonyl Condensation Reactions

Amines

Carbon-Carbon Bond Forming Reactions in Organic Synthesis

Pericyclic Reactions

Carbohydrates

Amino Acids and Proteins

Synthetic Polymers

Lipids

Filters

Both LiAlH₄ and NaBH₄ are reducing agents.Which statement about these reagents is true?