Question 1

What diseases are currently screened using nucleic acid tests?

Accepted Answer

A)  Hepatitis B and C viruses, West Nile virus, and HIV-1 
B)  Chagas disease, malaria, and syphilis 
C)  Hepatitis B virus, hepatitis C virus, and HIV 
D)  Human T-cell lymphotropic virus-I/human T-cell lymphotropic virus-II, HIV 1/HIV-2, and hepatitis C virus 
A)  Hepatitis B and C viruses, West Nile virus, and HIV-1 
B)  Chagas disease, malaria, and syphilis 
C)  Hepatitis B virus, hepatitis C virus, and HIV 
D)  Human T-cell lymphotropic virus-I/human T-cell lymphotropic virus-II, HIV 1/HIV-2, and hepatitis C virus A

Question 2

Which of the following patients should not receive cytomegalovirus (CMV)-positive blood?

Accepted Answer

A)  Premature infants 
B)  HIV-positive patients 
C)  Bone marrow recipients 
D)  Unborn infants of pregnant women who are seronegative 
E)  All of the above 
A)  Premature infants 
B)  HIV-positive patients 
C)  Bone marrow recipients 
D)  Unborn infants of pregnant women who are seronegative 
E)  All of the above E

Question 3

What is the advantage of testing donors' blood using nucleic acid test methods?

Accepted Answer

A)  Detection of small amounts of the virus 
B)  Reduction of costs involved in testing 
C)  Quicker and easier to perform than other methods 
D)  All of the above 
A)  Detection of small amounts of the virus 
B)  Reduction of costs involved in testing 
C)  Quicker and easier to perform than other methods 
D)  All of the above A

Question 4

What of the following measures is taken to prevent cytomegalovirus infection from blood units?

Accepted Answer

A)  Leukocyte reduction 
B)  Washing 
C)  Freezing and thawing 
D)  Nucleic acid testing 
A)  Leukocyte reduction 
B)  Washing 
C)  Freezing and thawing 
D)  Nucleic acid testing

Question 5

Persons who have had injections of human growth hormone are indefinitely deferred as blood donors.What disease is associated with the injections?

Accepted Answer

A)  Trypanosomiasis cruzi 
B)  Babesia microti 
C)  Borrelia burgdorferi 
D)  Creutzfeldt-Jakob disease 
A)  Trypanosomiasis cruzi 
B)  Babesia microti 
C)  Borrelia burgdorferi 
D)  Creutzfeldt-Jakob disease

Question 6

Which of the following diseases relies on obtaining a thorough donor history to reduce potential transmission in blood donors?

Accepted Answer

A)  Syphilis 
B)  Human T-cell lymphotropic virus-I 
C)  Cytomegalovirus 
D)  Malaria 
A)  Syphilis 
B)  Human T-cell lymphotropic virus-I 
C)  Cytomegalovirus 
D)  Malaria

Question 7

Which of the following characteristics is associated with human T-cell lymphotropic virus-I?

Accepted Answer

A)  It can be transmitted in blood products. 
B)  It is found in patients with tropical spastic paraparesis. 
C)  It is found in patients with adult T-cell leukemia. 
D)  All of the above 
A)  It can be transmitted in blood products. 
B)  It is found in patients with tropical spastic paraparesis. 
C)  It is found in patients with adult T-cell leukemia. 
D)  All of the above

Question 8

Which hepatitis virus is transmitted similar to hepatitis A?

Accepted Answer

A)  Hepatitis E virus 
B)  Hepatitis B virus 
C)  Hepatitis C virus 
D)  Hepatitis D virus 
A)  Hepatitis E virus 
B)  Hepatitis B virus 
C)  Hepatitis C virus 
D)  Hepatitis D virus

Question 9

What is the true statement regarding West Nile virus testing?

Accepted Answer

A)  Testing for West Nile virus is required only in New York and California. 
B)  Testing for West Nile virus is necessary only in the warmer months of the year. 
C)  West Nile virus testing is performed using nucleic acid testing on all donor units. 
D)  West Nile virus testing is optional. 
A)  Testing for West Nile virus is required only in New York and California. 
B)  Testing for West Nile virus is necessary only in the warmer months of the year. 
C)  West Nile virus testing is performed using nucleic acid testing on all donor units. 
D)  West Nile virus testing is optional.

Question 10

Which of the following blood products is tested for bacterial contamination following storage?

Accepted Answer

A)  Cryoprecipitated AHF 
B)  Red blood cells, frozen 
C)  Platelets 
D)  Fresh frozen plasma 
A)  Cryoprecipitated AHF 
B)  Red blood cells, frozen 
C)  Platelets 
D)  Fresh frozen plasma

Question 11

What is the significance of a positive RPR test for syphilis?

Accepted Answer

A)  Antibodies to Treponema pallidum are present 
B)  Past or present venereal disease infection 
C)  Possibility of an infection with Treponema pallidum 
D)  Antigens associated with venereal disease are present 
A)  Antibodies to Treponema pallidum are present 
B)  Past or present venereal disease infection 
C)  Possibility of an infection with Treponema pallidum 
D)  Antigens associated with venereal disease are present

Question 12

Why is Hepatitis A virus transmission in blood unusual?

Accepted Answer

A)  Hepatitis A virus is usually transmitted by the enteric route 
B)  Hepatitis A virus is usually an acute hepatitis 
C)  Infectivity after a hepatitis A virus infection is usually only 2 weeks 
D)  All of the above 
A)  Hepatitis A virus is usually transmitted by the enteric route 
B)  Hepatitis A virus is usually an acute hepatitis 
C)  Infectivity after a hepatitis A virus infection is usually only 2 weeks 
D)  All of the above

Question 13

When are surrogate marker tests useful?

Accepted Answer

A)  When the required test is too expensive 
B)  When direct testing is not yet available 
C)  When the required test detects too many false-positive results 
D)  When the internal controls are not valid 
A)  When the required test is too expensive 
B)  When direct testing is not yet available 
C)  When the required test detects too many false-positive results 
D)  When the internal controls are not valid

Question 14

Define a hepatitis B virus carrier.

Accepted Answer

A)  Hepatitis B surface antigen-positive person who has liver disease because of a previous hepatitis exposure 
B)  Person who can transmit hepatitis B virus but may not be outwardly affected by it 
C)  Hepatitis B surface antibody-positive person, negative for hepatitis B surface antigen 
D)  Hepatitis B core antibody-positive person, negative for hepatitis B surface antigen 
A)  Hepatitis B surface antigen-positive person who has liver disease because of a previous hepatitis exposure 
B)  Person who can transmit hepatitis B virus but may not be outwardly affected by it 
C)  Hepatitis B surface antibody-positive person, negative for hepatitis B surface antigen 
D)  Hepatitis B core antibody-positive person, negative for hepatitis B surface antigen

Question 15

If a donor is positive for hepatitis C virus by nucleic acid testing,why is the process of "look-back" initiated?

Accepted Answer

A)  To quarantine units in the blood center that may exist from prior donations from the inventory 
B)  To notify recipients who may have previously received blood from this donor 
C)  To locate and quarantine units sent to transfusion facilities from this donor in the past 
D)  All of the above 
A)  To quarantine units in the blood center that may exist from prior donations from the inventory 
B)  To notify recipients who may have previously received blood from this donor 
C)  To locate and quarantine units sent to transfusion facilities from this donor in the past 
D)  All of the above

Question 16

Some donor centers have implemented the practice of diverting the first few milliliters of blood collected into a pouch attached to the collection bag.What is the purpose of this procedure?

Accepted Answer

A)  Reduce leukocyte contamination 
B)  Prepare pedipacks for neonates 
C)  Avoid bacterial contamination 
D)  Collect blood for viral testing 
A)  Reduce leukocyte contamination 
B)  Prepare pedipacks for neonates 
C)  Avoid bacterial contamination 
D)  Collect blood for viral testing

Question 17

What is the most sensitive test for HIV?

Accepted Answer

A)  Enzyme-linked assays 
B)  Chemiluminescence 
C)  Western blot 
D)  Nucleic acid 
A)  Enzyme-linked assays 
B)  Chemiluminescence 
C)  Western blot 
D)  Nucleic acid

Question 18

How is the sensitivity of a viral marker assay described?

Accepted Answer

A)  True positives divided by difference between true positives and false negatives 
B)  True negatives divided by sum of true negatives and false positives 
C)  True positives divided by sum of true positives and false negatives 
D)  True negatives divided by difference between true negatives and false positives 
A)  True positives divided by difference between true positives and false negatives 
B)  True negatives divided by sum of true negatives and false positives 
C)  True positives divided by sum of true positives and false negatives 
D)  True negatives divided by difference between true negatives and false positives

Question 19

What is the most common mode of transmission for hepatitis C virus?

Accepted Answer

A)  Contaminated food and water 
B)  Transfusion 
C)  Sexual transmission 
D)  Intravenous drug use 
A)  Contaminated food and water 
B)  Transfusion 
C)  Sexual transmission 
D)  Intravenous drug use

Question 20

Which of the following is the most common transfusion-transmitted infection?

Accepted Answer

A)  AIDS 
B)  Syphilis 
C)  Cytomegalovirus 
D)  Hepatitis 
A)  AIDS 
B)  Syphilis 
C)  Cytomegalovirus 
D)  Hepatitis

What diseases are currently screened using nucleic acid tests?

Which of the following patients should not receive cytomegalovirus (CMV)-positive blood?

What is the advantage of testing donors' blood using nucleic acid test methods?

What of the following measures is taken to prevent cytomegalovirus infection from blood units?

Persons who have had injections of human growth hormone are indefinitely deferred as blood donors.What disease is associated with the injections?

Which of the following diseases relies on obtaining a thorough donor history to reduce potential transmission in blood donors?

Which of the following characteristics is associated with human T-cell lymphotropic virus-I?

Which hepatitis virus is transmitted similar to hepatitis A?

What is the true statement regarding West Nile virus testing?

Which of the following blood products is tested for bacterial contamination following storage?

What is the significance of a positive RPR test for syphilis?

Why is Hepatitis A virus transmission in blood unusual?

When are surrogate marker tests useful?

Define a hepatitis B virus carrier.

If a donor is positive for hepatitis C virus by nucleic acid testing,why is the process of "look-back" initiated?

Some donor centers have implemented the practice of diverting the first few milliliters of blood collected into a pouch attached to the collection bag.What is the purpose of this procedure?

What is the most sensitive test for HIV?

How is the sensitivity of a viral marker assay described?

What is the most common mode of transmission for hepatitis C virus?

Which of the following is the most common transfusion-transmitted infection?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters

Exam 14: Testing of Donor Blood

What diseases are currently screened using nucleic acid tests?

Which of the following patients should not receive cytomegalovirus (CMV)-positive blood?

What is the advantage of testing donors' blood using nucleic acid test methods?

What of the following measures is taken to prevent cytomegalovirus infection from blood units?

Persons who have had injections of human growth hormone are indefinitely deferred as blood donors.What disease is associated with the injections?

Which of the following diseases relies on obtaining a thorough donor history to reduce potential transmission in blood donors?

Which of the following characteristics is associated with human T-cell lymphotropic virus-I?

Which hepatitis virus is transmitted similar to hepatitis A?

What is the true statement regarding West Nile virus testing?

Which of the following blood products is tested for bacterial contamination following storage?

What is the significance of a positive RPR test for syphilis?

Why is Hepatitis A virus transmission in blood unusual?

When are surrogate marker tests useful?

Define a hepatitis B virus carrier.

If a donor is positive for hepatitis C virus by nucleic acid testing,why is the process of "look-back" initiated?

Some donor centers have implemented the practice of diverting the first few milliliters of blood collected into a pouch attached to the collection bag.What is the purpose of this procedure?

What is the most sensitive test for HIV?

How is the sensitivity of a viral marker assay described?

What is the most common mode of transmission for hepatitis C virus?

Which of the following is the most common transfusion-transmitted infection?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters