Exam 16: Integration of Metabolism

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What is meant by the term ketoacidosis?

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Insulin resistance is __________.

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Dieters frequently fast in an attempt to reduce their weight. During these fasts, they often lose considerable muscle mass rather than fat. Explain.

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What is a phorbol ester?

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What is meant by the term GLUT4?

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The biological effects of atrial natriuretic factor appear to be mediated by __________.

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Which of the following molecules is a second messenger?

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Urea synthesis is the responsibility of which organ of the body?

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The brain consumes about __________% of the body's energy.

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Hemoglobin molecules exposed to high levels of glucose are converted to glycated products. The most common, referred to as hemoglobin A1c (HbA1c), contains a chain glycated adduct. Because red blood cells last about 3 months, HbA1c concentration is a useful measure of a patient's blood sugar control. In general terms describe why and how HbA1c forms.

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What is a tumor promoter?

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During periods of fasting some muscle protein is depleted. How is this process initiated, and what happens to the amino acids in the proteins?

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Skeletal muscle cannot synthesize fatty acids yet it produces the enzyme acetyl-CoA carboxylase. Explain the role of this enzyme.

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28 The organ responsible for the regulation of blood pH is __________.

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Receptor tyrosine kinases are transmembrane receptors that bind ligands such as __________.

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Which of the following molecules do GPCRs not respond to?

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List three examples of steroid transport proteins.

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Animals employing several mechanisms to prevent excessive hormone action and release. Examples include which of the following?

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In animals, the vast majority of water-soluble hormones are __________.

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Leptin is secreted by which of the following tissues?

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