Exam 2: Communication Within the Nervous System
Who was Otto Loewi,and what were his major findings? Describe the experiment he ran to prove that the synapse was a chemical connection.
Otto Loewi was a German-born pharmacologist and Nobel Prize winner who is best known for his discovery of chemical neurotransmission. His major finding was the demonstration that nerve impulses are transmitted by means of chemical substances, or neurotransmitters, rather than by electrical impulses alone.
Loewi's groundbreaking experiment, which he conducted in 1921, involved two frog hearts. He first stimulated the vagus nerve of one frog's heart, causing it to slow down. He then collected the fluid surrounding the heart and transferred it to the second frog's heart, which also slowed down. This demonstrated that the chemical released by the stimulated nerve was responsible for the change in heart rate, proving that the synapse was a chemical connection.
This experiment provided the first evidence for the existence of chemical neurotransmission and laid the foundation for our understanding of how nerve cells communicate with each other. Loewi's work revolutionized the field of neuroscience and has had a lasting impact on our understanding of the nervous system.
___ are released from axon terminals and are detected by receptors on an adjacent neuron.
B
Which of the following is true of autoreceptors?
B
A neuron that transmits information between the central nervous system and a muscle is called a(n):
Local anesthetics work via ___ while general anesthetics have the effect of ___.
Which of the statements about cell membranes is not correct?
Which of the following statements regarding the absolute refractory period is false?
Substance P is an inhibitory neurotransmitter in the lower brain.
The sodium-potassium pumps of a neuron are major consumers of energy.
A brief,rapid reversal of the neuron's potential from -70mV to +30 or +40mV and back indicates:
Which of the following statements regarding nicotinic receptors is false?
If postsynaptic potentials arrive at the same location but a short time apart,___ will occur.
In the nervous system,which of the following types of cells is most numerous?
A movement of the resting membrane potential from -70 mV to -65 mV would be termed a(n):
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