Exam 2: Signaling Within Neurons

What best describes current?

Changes in ion conductance or ion concentration can alter the resting membrane potential of a cell. For each of the following, write in the letter indicating whether each condition would cause hyperpolarization (H), depolarization (D), or very little change (LC) in the resting membrane potential, and the reason for this change. Condition Membrane potential change Reason ncrease in ----------- ----------- increase in ----------- ----------- increase in permeability ----------- ----------- increase in permeability ----------- -----------

Reconstruct an action potential starting with the resting potential and ending with the voltage across the membrane coming back to rest after the action potential. Describe single channel behavior, whole cell current and/or conductance, and changes in voltage with respect to the equilibrium potential for each ion.?

What is an RC circuit? Choose all that apply.

You are in a lab and conduct a patch clamp experiment (Figure Q2-39) in which you change the voltage across the membrane by +20 mV (top trace). You record the resulting single channel current (lower three traces). Based on these single channel currents, what do you think the whole-cell current would look like? Figure Q2-39