Which of the Following Is True About the Holoenzyme in an Open

Multiple Choice

Which of the following is true about the holoenzyme in an open complex?

A) The DNA is bound mainly to the sigma-subunit.
B) There no interaction between the sigma factor and the -10 region.
C) There are two Na⁺ ions in the core enzyme .
D) Region 2.4 of the sigma-factor binds to the -35 region.
E) The DNA is bound mainly to the sigma-subunit and there no interaction between the sigma factor and the -10 region are both true.