Which of These Could Be a Cause of Hypertrophy of the Adrenal

Multiple Choice

Which of these could be a cause of hypertrophy of the adrenal cortex?

A) autoimmune destruction of receptors for adrenocorticotropic hormone (ACTH)
B) autoimmune destruction of hypothalamic cells that secrete cortotropin-releasing hormone
C) injection of an excess of cortisol
D) destruction of the anterior pituitary by a stroke
E) excessively rapid clearance of cortisol from the circulation