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Dominant Mutant Forms of IFNγR1 Exhibit All of the Following

Question 42

Multiple Choice

Dominant mutant forms of IFNγR1 exhibit all of the following in heterozygotes except _____.


A) they are recycled by endocytosis more quickly than the normal receptor
B) the cytoplasmic tail is truncated
C) they are able to form stable dimers with the normal form
D) they cause less severe immunodeficiency than do the homozygous recessive forms
E) they are unable to transduce signals when bound to the normal form.

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