Chronic Granulomatous Disease (CGD),a Condition Resulting in Chronic Bacterial and Fungal

Multiple Choice

Chronic granulomatous disease (CGD) ,a condition resulting in chronic bacterial and fungal infections,is caused by one or more defects in _____,compromising the ability of macrophages to _____.

A) CD18; produce cell adhesion molecules
B) NADPH oxidase; produce superoxide radical (O₂^-)
C) CD40 ligand; produce GM-CSF
D) C5-C9; defend against Neisseria
E) C3; opsonize capsulated bacteria.