Hinda Mundy,26 Years Old,grew Concerned When a Lump Appeared in Her

Multiple Choice

Hinda Mundy,26 years old,grew concerned when a lump appeared in her lower neck and she had pain in her chest and a dry cough.She also told her physician that she had experienced fatigue,night sweats,unintentional weight loss,pruritis (dry,itchy skin) ,and intermittent fevers over the past few months.Immunohistological staining of a biopsy of the enlarged lymph node revealed the presence of large multinucleated Reed-Sternberg cells.Polymerase chain reaction (PCR) tests confirmed immunoglobulin gene rearrangements; however,B-cell antigen expression was absent.Hinda entered complete remission after treatment with four cycles of chemotherapy combined with radiotherapy.These symptoms and treatment are most consistent with a diagnosis of

A) Hodgkin's lymphoma
B) multiple myeloma
C) acute lymphoblastic leukemia (ALL)
D) Waldenström's magroglobulinemia
E) chronic lymphocytic leukemia (CLL) .