Genomewide Association (GWA) Studies Have Identified Common Single Nucleotide DNA

Multiple Choice

Genomewide association (GWA) studies have identified common single nucleotide DNA variants that are very rarely of even moderate effect and that are collectively insufficient to explain the genetic variance of complex diseases. Which of the following can at least partly explain the genetic variance?

A) Rare single nucleotide variants.
B) de novo variants.
C) Copy number variants.
D) Gene-gene interactions