With Regard to Affected Sib Pair (ASP) Analysis Which, If

Multiple Choice

With regard to affected sib pair (ASP) analysis which, if any, of the following statements is true.

A) ASP analysis is a type of parametric linkage analysis that is popularly used to study complex diseases.
B) It is highly convenient because samples are required from the affected sibs only and samples from just 100 affected sib pairs are usually enough to obtain decent results.
C) It is less suited to studying complex disease where the relative risk of disease is low.
D) A lod score of 3 is highly significant evidence for linkage in ASP analysis.