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When a gene is expressed, the two DNA strands are locally unwound to allow access by the ____1_____ machinery. One of the DNA strands serves as a ____2____ for an RNA polymerase to synthesize a complementary RNA. The initial transcript, often called the ____3____ transcript, is identical in base sequence (except that U replaces T) to the sequence of the other DNA strand, which is known as the ____4____ strand (and so the opposing strand that serves as the ___2____ is also known as the ____5____ strand). The segment of genomic DNA that corresponds to the ____3____ transcript is known as the ___6___ ___7____.

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