A Plant-Derived Protein Known as Colchicine Can Be Used to Poison

Multiple Choice

A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the mitotic spindle.Which of the following would result if colchicine is added to a sample of cells in G₂?

A) The cells would immediately die.
B) The cells would be unable to begin M,and the cell cycle would arrest in G₂.
C) The nuclear membrane would break down,but chromosomes would fail to condense and the cell cycle would arrest in early prophase.
D) Chromosomes would condense but fail to align at the metaphase plate,and the cell cycle would arrest at this point.