The Free-Energy Change for the Hydrolysis of ATP to ADP

Multiple Choice

The free-energy change for the hydrolysis of ATP to ADP + ℗_i,under standard conditions (1 M concentration of both reactants and products) is -7.3 kcal/mol.However,in the cytoplasm of the cell,the free-energy change is about -13 kcal/mol.Based on this observation,what would you predict the free-energy change for the reverse reaction (formation of ATP from ADP and ℗_i) would be under cellular conditions?

A) about +7.3 kcal/mol
B) less than +7.3 kcal/mol
C) about +13 kcal/mol
D) about +26 kcal/mol