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Assume That Defects in a Hypothetical Gene X Have Been

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Assume that defects in a hypothetical gene X have been linked to a disease.Two copies of a defective gene X will predispose a child to the disease, while a single copy of the gene seems to produce no symptoms.Because early treatment can counteract the effects of the disease, a program of voluntary genetic testing is being performed with prospective parents.Caril Ann is pregnant with Charles's child.You obtain DNA samples from Charles, Caril Ann, and the fetus.You conduct PCR from these DNA samples using two different primer sets that will detect two commonly found deletions in gene X that are associated with the disease.The gene and location of these primer sets are shown in Figure 10-61A.Your results are shown in Figure 10-61B. (A)
Assume that defects in a hypothetical gene X have been linked to a disease.Two copies of a defective gene X will predispose a child to the disease, while a single copy of the gene seems to produce no symptoms.Because early treatment can counteract the effects of the disease, a program of voluntary genetic testing is being performed with prospective parents.Caril Ann is pregnant with Charles's child.You obtain DNA samples from Charles, Caril Ann, and the fetus.You conduct PCR from these DNA samples using two different primer sets that will detect two commonly found deletions in gene X that are associated with the disease.The gene and location of these primer sets are shown in Figure 10-61A.Your results are shown in Figure 10-61B. (A) (B) Figure 10-61 A.Which of the three individuals have defects in gene X? B.Which individuals have a single defective gene and which have two defective copies of the gene? C.Indicate the location of each individual's defects on gene X.

(B)
Assume that defects in a hypothetical gene X have been linked to a disease.Two copies of a defective gene X will predispose a child to the disease, while a single copy of the gene seems to produce no symptoms.Because early treatment can counteract the effects of the disease, a program of voluntary genetic testing is being performed with prospective parents.Caril Ann is pregnant with Charles's child.You obtain DNA samples from Charles, Caril Ann, and the fetus.You conduct PCR from these DNA samples using two different primer sets that will detect two commonly found deletions in gene X that are associated with the disease.The gene and location of these primer sets are shown in Figure 10-61A.Your results are shown in Figure 10-61B. (A) (B) Figure 10-61 A.Which of the three individuals have defects in gene X? B.Which individuals have a single defective gene and which have two defective copies of the gene? C.Indicate the location of each individual's defects on gene X.

Figure 10-61
A.Which of the three individuals have defects in gene X?
B.Which individuals have a single defective gene and which have two defective copies of the gene?
C.Indicate the location of each individual's defects on gene X.

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A.All three are affected.
B.The two pare...

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