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The BRCA2 Protein Functions in Double-Strand Break Repair

Question 8

Multiple Choice

The BRCA2 protein functions in double-strand break repair.If a woman is heterozygous for a loss-of-function allele of BRCA2, she


A) will develop cancer because two functional copies of BRCA2 are needed in every cell.
B) will not get cancer because BRCA1 can compensate for the loss of BRCA2.
C) will develop cancer after several mutations occur, even if the mutations occur in different clonal populations of cells.
D) may develop cancer because mutation of the wild-type BRCA2 allele could destroy an important DNA repair mechanism.

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