What Is One Current Limitation of Whole-Genome Sequencing for Personalized

Multiple Choice

What is one current limitation of whole-genome sequencing for personalized cancer treatment?

A) The human genome is too large to be sequenced for individual patients.
B) Drugs may not exist to target the mutant genes that are identified.
C) Whole-genome sequencing reveals only mutations in coding sequences, and regulatory mutations may also be important.
D) The genomes of cells with abnormal karyotypes, such as cancer cells, cannot be sequenced reliably.