How Are Open Reading Frames or Exons Predicted from Genomic

Multiple Choice

How are open reading frames or exons predicted from genomic sequence?

A) If the open reading frame is at least 10 sense codons long, it is considered an exon.
B) If the sequence is absent from mRNA, it is considered an exon.
C) If there is a splice donor and acceptor site at the ends of the open reading frame, it is considered an exon.
D) If an open reading frame is longer than 21 sense codons, it is predicted to be an exon.
E) If an enhancer and promoter sequence are present, the downstream sequence is considered an exon.