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What Do You Predict Would Be the Effect of an Inversion

Question 18

Multiple Choice

What do you predict would be the effect of an inversion of the β-globin gene cluster with respect to the LCR?


A) No globin genes will be expressed and the fetus will die in utero.
B) ε-globin will be expressed first during development.
C) The order of globin gene expression will be reversed; the effect on the fetus cannot be predicted.
D) The individual will develop sickle-cell disease in adult life.

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