Consider the Way Alternative Splicing Leads to the Production of the Small

Multiple Choice

Consider the way alternative splicing leads to the production of the small t antigen and the large T antigen in the mammalian virus SV40. What would be the result of a mutation that occurred in the gene that encodes the SF2 protein?

A) Higher amounts of the small t antigen would be produced.
B) Use of the first 5ʹ splice site would be favored over the second 5ʹ splice site.
C) The large T antigen would be produced but at lower than normal levels.
D) Both the first and second 5ʹ splice sites could be used, but the second would be favored over the first.
E) Regions A, B, and C would all be transcribed and translated to produce the correct antigen.