Essay
In the general population, 1 in 300 individuals is a carrier for Tay- Sachs disease, while 1 in 30 individuals of Ashkenazi Jew descent are carriers. Tay- Sachs also affects 1 in 30 individuals with French- Canadian ancestry, although two completely unique mutations are responsible for the Ashkenazi and French- Canadian mutations.
What are the chances of two individuals who are carriers having a child with Tay- Sachs if
a. both individuals are not of Ashkenazi or French- Canadian descent?
b. one individual is of Ashkenazi descent and the other is from the general population?
c. both individuals are of Ashkenazi descent?
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