What Are the Typical Consequences of Mutations in Keratins and Their

Multiple Choice

What are the typical consequences of mutations in keratins and their associated proteins?

A) Neurodegeneration as a result of interference with normal axonal transport.
B) Muscle development defects as a result of sarcomere disorganization.
C) Skeletal and cardiac abnormalities as a result of a weakened nuclear envelope.
D) Cornea disorders as a result of cell rupture from mechanical trauma.
E) Developmental defects as a result of abnormal signaling related to the primary cilia.