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Exhibit 6A This Is a Reaction Going on in Your

Question 17

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Exhibit 6A This is a reaction going on in your muscle cells right this very minute: Exhibit 6A This is a reaction going on in your muscle cells right this very minute:   The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:   Typical cellular concentrations: triose phosphate isomerase = 0.1 nM Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM Refer to Exhibit 6A.  Hindrate  is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.1 nM, the enzyme's K<sub>M</sub> for the substrate is unchanged, but the apparent V<sub>max</sub> is altered to 50 nM\sec. A)  This is a competitive inhibitor. B)  This is an uncompetitive inhibitor. C)  This is a noncompetitive inhibitor. D)  This is an irreversible inhibitor. The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics: Exhibit 6A This is a reaction going on in your muscle cells right this very minute:   The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:   Typical cellular concentrations: triose phosphate isomerase = 0.1 nM Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM Refer to Exhibit 6A.  Hindrate  is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.1 nM, the enzyme's K<sub>M</sub> for the substrate is unchanged, but the apparent V<sub>max</sub> is altered to 50 nM\sec. A)  This is a competitive inhibitor. B)  This is an uncompetitive inhibitor. C)  This is a noncompetitive inhibitor. D)  This is an irreversible inhibitor.
Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A. "Hindrate" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.1 nM, the enzyme's KM for the substrate is unchanged, but the apparent Vmax is altered to 50 nM\sec.


A) This is a competitive inhibitor.
B) This is an uncompetitive inhibitor.
C) This is a noncompetitive inhibitor.
D) This is an irreversible inhibitor.

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