Question 1

What is the potential effect in a tube agglutination test if a red cell suspension with a concentration greater than 5% is used?

Accepted Answer

A)   False negatives
B)   False positives
C)   Hemolysis
D)   No effect A

Question 2

What biological molecules are considered the most immunogenic?

Accepted Answer

A)   Carbohydrates
B)   Lipids
C)   Proteins
D)   Enzymes C

Question 3

Select the term from the list below that best fits the definitions.
-Part of the antigen that the immunoglobulin binds to

Accepted Answer

A)  Kappa
B)  Epitope
C)  Hinge region
D)  Isotype
E)  Idiotype B

Question 4

Which immunoglobulin class is impacted by the zeta potential in a hemagglutination test?

Accepted Answer

A)   IgM
B)   IgG
C)   IgA
D)   IgE

Question 5

Select the term from the list below that best fits the definitions.
-One of the two types of light chains

Accepted Answer

A)  Kappa
B)  Epitope
C)  Hinge region
D)  Isotype
E)  Idiotype

Question 6

A technologist added 4 drops of a 5% red cell suspension instead of the required 1 drop to a hemagglutination test.What is the potential consequence to the test results?

Accepted Answer

A)   False-positive
B)   False-negative
C)   Hemolysis due to complement activation
D)   Test results are not affected

Question 7

MATCHING
Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once.
-Found in secretions,such as breast milk

Accepted Answer

A)  IgA
B)  IgM
C)  IgG
D)  IgE

Question 8

Select the portion of the antibody molecule that imparts the antibody's unique class function.

Accepted Answer

A)   Constant region of the heavy chain
B)   Constant region of the light chain
C)   Variable region of the heavy chain
D)   Variable region of the light chain

Question 9

MATCHING
Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once.
-Associated with intravascular cell destruction

Accepted Answer

A)  IgA
B)  IgM
C)  IgG
D)  IgE

Question 10

Hemolysis was observed at room temperature when testing a patient's serum with reagent red cells used for screening.When this test was repeated using the patient's plasma,no hemolysis was observed.What was the most likely explanation for the different reactions?

Accepted Answer

A)   The plasma sample was collected incorrectly.
B)   The serum sample was contaminated.
C)   Complement activation was inhibited by calcium in the plasma sample.
D)   The serum sample was fresher.

Question 11

Select the cell involved in humoral immunity.

Accepted Answer

A)   Neutrophils
B)   T lymphocytes
C)   B lymphocytes
D)   Monocytes

Question 12

Select the term from the list below that best fits the definitions.
-Imparts flexibility to the immunoglobulin molecule

Accepted Answer

A)  Kappa
B)  Epitope
C)  Hinge region
D)  Isotype
E)  Idiotype

Question 13

MATCHING
Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once.
-Efficient in activation of the complement cascade

Accepted Answer

A)  IgA
B)  IgM
C)  IgG
D)  IgE

Question 14

MATCHING
Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once.
-Able to cross the placenta

Accepted Answer

A)  IgA
B)  IgM
C)  IgG
D)  IgE

Question 15

Extravascular destruction of blood cells occurs in the:

Accepted Answer

A)   blood vessels.
B)   lymph nodes.
C)   spleen.
D)   thymus.

Question 16

What process is described by opsonization?

Accepted Answer

A)   Lysis of cells
B)   Binding to cells or antigens
C)   Ingestion of cells
D)   Phagocytosis

Question 17

MATCHING
Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once.
-Associated with allergic reactions and mast cell activation

Accepted Answer

A)  IgA
B)  IgM
C)  IgG
D)  IgE

Question 18

Select the term from the list below that best fits the definitions.
-The type of immunoglobulins determined by the heavy chain

Accepted Answer

A)  Kappa
B)  Epitope
C)  Hinge region
D)  Isotype
E)  Idiotype

Question 19

Select the immunoglobulin class produced first in the primary immune response.

Accepted Answer

A)   IgG
B)   IgE
C)   IgA
D)   IgM

Question 20

Which of the following will cause an antigen to elicit a greater immune response?

Accepted Answer

A)   Small antigen size
B)   Composed largely of carbohydrates
C)   Size greater than 10,000 daltons
D)   Similarity to the host

Exam 2: Immunology: Basic Principles and Applications in the Blood Bank

What is the potential effect in a tube agglutination test if a red cell suspension with a concentration greater than 5% is used?

What biological molecules are considered the most immunogenic?

Select the term from the list below that best fits the definitions. -Part of the antigen that the immunoglobulin binds to

Which immunoglobulin class is impacted by the zeta potential in a hemagglutination test?

Select the term from the list below that best fits the definitions. -One of the two types of light chains

A technologist added 4 drops of a 5% red cell suspension instead of the required 1 drop to a hemagglutination test.What is the potential consequence to the test results?

MATCHING Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Found in secretions,such as breast milk

Select the portion of the antibody molecule that imparts the antibody's unique class function.

MATCHING Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Associated with intravascular cell destruction

Hemolysis was observed at room temperature when testing a patient's serum with reagent red cells used for screening.When this test was repeated using the patient's plasma,no hemolysis was observed.What was the most likely explanation for the different reactions?

Select the cell involved in humoral immunity.

Select the term from the list below that best fits the definitions. -Imparts flexibility to the immunoglobulin molecule

MATCHING Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Efficient in activation of the complement cascade

MATCHING Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Able to cross the placenta

Extravascular destruction of blood cells occurs in the:

What process is described by opsonization?

MATCHING Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Associated with allergic reactions and mast cell activation

Select the term from the list below that best fits the definitions. -The type of immunoglobulins determined by the heavy chain

Select the immunoglobulin class produced first in the primary immune response.

Which of the following will cause an antigen to elicit a greater immune response?