Why Are Proteolytic Enzymes Not Used in the Routine Screening

Multiple Choice

Why are proteolytic enzymes not used in the routine screening for antibodies?

A) The reagent is too expensive for routine use.
B) Clinically insignificant antibodies are enhanced.
C) Red cells must be treated with enzymes first, which makes this technique impractical.
D) Some antigens are destroyed by enzymes, which would cause the antibodies to be missed.