Question 1

Which of the following teratogens is most commonly known for stunted limb growth?

Accepted Answer

A)   ACE Inhibitors
B)   Thalidomide
C)   Amphotericin
D)   Isoretinoin B

Question 2

When is the most critical time period for development and also the most dangerous time to use teratogens?

Accepted Answer

A)   Three weeks prior to conception- Four weeks after last menstrual period
B)   Four weeks after last menstrual period- Fifteen weeks after last menstrual period
C)   Fifteen weeks after last menstrual period- 25 weeks after last menstrual period
D)   The three weeks prior to the delivery of the baby B

Question 3

During organogenesis the cells of the ICM (intercellular mass) create the ectoderm, mesoderm, and ectoderm. Which of the following organs and tissues are associated with development of the endoderm?

Accepted Answer

A)   Bone, cartilage and blood
B)   Brain, spinal cord and retina
C)   Liver, pancreas, and blood vessels
D)   Gallbladder, bladder, and respiratory system lining D

Question 4

A 25-year-old Caucasian Female presents to the office and is going over her History she reports she does not remember her LMP and states she may be pregnant. She gives you a list of her Medications she is currently taking. Which of the following of her medications is a teratogen and needs to be discontinued?

Accepted Answer

A)   Griseofulvin
B)   Phenergan
C)   Acetaminophen
D)   Hydrocortisone cream

Question 5

DES was taken during pregnancies to alleviate high risks however it caused some severe side effects for the fetus. Which of the following accurately describes the side effect of Diethylstilbesterol use during pregnancy?

Accepted Answer

A)   Microcephaly and Congenital Heart Defects
B)   Structural abnormalities of Vagina, Cervix and Gonads
C)   Absent Limbs or Stunted Limb growth
D)   Low Birth weight and Single Palmar crease

Question 6

What criteria must be met to have HELLP syndrome during pregnancy?

Accepted Answer

A)   HTN, Elevated protein, Hemolysis, Elevated Liver Enzymes, and Low Platelets
B)   Hemolysis, Ecchymosis, Lactate dehydrogenase deficiency and Low Platelets
C)   High blood pressure, Elevated Protein, Seizure activity and Low Platelets
D)   Hyperthermia, Elevated Proteins, and Low Platelets

Question 7

At time of delivery a 1-day-old female neonate on physical exam is found to have microcephaly and a diffuse spread red rash which of the following is highest on your differential diagnosis list?

Accepted Answer

A)   CMV
B)   FAS
C)   Rubella
D)   Roseola'

Question 8

During embryonic development it describes the time period and cells made up from time period of fertilization until the embryo gets implanted into the uterine wall. Which of the following is a correct description of cells and timeline of embryogenesis?

Accepted Answer

A)   After fertilization the zygote undergoes rapid division is called a blastocyst
B)   The ICM cells flatten and become a ring of cells termed a morula
C)   Fluid accumulates inside the rapidly cleaved cells and creates a hollow sphere called a blastocyte
D)   The group of cells that develop further to deliver fetal nutrients is called a trophoblast

Question 9

What is the most common characteristic feature of a child whose mother ingested ethyl alcohol at some time during pregnancy and the child has FAS?

Accepted Answer

A)   Craniofacial abnormality and Behavior disturbances
B)   Spinal Defects and Increased Birth Weight
C)   Cardiac Defects and Stunted Limb Growth
D)   Behavior disturbances and Seizure activity

Question 10

What is the most frequently documented pregnancy complication for cocaine users?

Accepted Answer

A)   Visual Defects
B)   Placental Abruption
C)   Loss of Reproducibility
D)   Low Birth weight

Exam 4: Development and Teratogenesis