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What Is Currently the BEST Explanation for What Determines Whether

Question 1

Multiple Choice

What is currently the BEST explanation for what determines whether a T cell develops into a CD8+ T cell or a CD4+ T cell?


A) CD4/TCR coengagement suppresses CD8 expression, and CD8/TCR coengagement suppresses CD4 expression.
B) T cells randomly downregulate CD4 or CD8, and only cells that still bind the appropriate MHC will get a strong enough signal to survive.
C) CD4 or CD8 expression is determined by the strength and duration of the TCR/MHC interaction.
D) CD4 or CD8 expression is predestined in the bone marrow.
E) Only ?? T cells express CD8.

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