Which of the Following BEST Encapsulates the Findings of the Hozumi

Multiple Choice

Which of the following BEST encapsulates the findings of the Hozumi and Tonegawa experiments?

A) Every possible light chain that could be formed, in terms of receptor specificity, is encoded by a separate gene within the human genome.
B) Light chains are produced by means of somatic rearrangement of germ-line DNA in B cells.
C) The different light-chain variable regions are produced by means of alternative splicing of pre-mRNA that has been transcribed from a fixed, unchanging DNA sequence.
D) Different light chains, each with unique specificity, are produced via the activity of alternative transcription factors that regulate antibody production at the level of transcription initiation.
E) None of the answers are correct.