Question 1

The most common symptom of degenerative joint disease is:

Accepted Answer

A)   Fever
B)   Swelling
C)   Pain
D)   Ankylosis
E)   Crepitation C

Question 2

The central ("midshaft")portion of long bones is called:

Accepted Answer

A)   Epiphysis
B)   Metaphysis
C)   Diaphysis
D)   Physis
E)   Anapophysis C

Question 3

Osteoporosis is usually diagnosed by means of:

Accepted Answer

A)   Bone biopsy
B)   Electron microscopy
C)   X-ray examination
D)   Analysis of blood
E)   Analysis of joint fluid C

Question 4

Patients with so-called seropositive rheumatoid arthritis have in their blood antibodies to:

Accepted Answer

A)   Viruses
B)   Their own immunoglobulins
C)   Smooth muscle cells
D)   Cartilage
E)   Synovial membrane

Question 5

Osteosarcomas most often arise in the bones of the:

Accepted Answer

A)   Skull
B)   Vertebrae
C)   Fingers
D)   Toes
E)   Knee

Question 6

The excess of which hormone causes osteoporosis?

Accepted Answer

A)   Androgens
B)   Estrogens
C)   Corticosteroids
D)   Prolactin
E)   Glucagon

Question 7

Migratory arthritis caused by Borrelia burgdorferi is typical of:

Accepted Answer

A)   Rocky Mountain spotted fever
B)   Trench foot
C)   Lyme disease
D)   Legionnaire's disease
E)   Osteoarthritis

Question 8

Osteogenesis imperfecta is an inborn error in the synthesis of:

Accepted Answer

A)   Collagen type I
B)   Collagen type II
C)   Collagen type III
D)   Phosphate crystals
E)   Basement membranes

Question 9

Subcutaneous nodules composed of a central area of fibrinoid necrosis surrounded by macrophages and lymphocytes are typical of:

Accepted Answer

A)   Infectious arthritis
B)   Rheumatoid arthritis
C)   Osteoarthritis
D)   Gout
E)   Rickets

Question 10

The most common primary malignant tumor of bones is called:

Accepted Answer

A)   Osteosarcoma
B)   Chondrosarcoma
C)   Paget's disease
D)   Ewing's disease
E)   Giant cell tumor of bone

Question 11

The extracellular organic matrix of bones is called:

Accepted Answer

A)   Osteon
B)   Osteoid
C)   Osteoblast
D)   Osteocyte
E)   Osteoclast

Question 12

A tumor in a 15-year-old boy was diagnosed in the diaphysis of the tibia.On x-ray examination,it had a sunburst appearance and histologically it was composed of a uniform population of small blue cells.This tumor is a(n):

Accepted Answer

A)   Osteosarcoma
B)   Chondrosarcoma
C)   Giant cell tumor
D)   Ewing's sarcoma
E)   Metastasis from a lung cancer

Question 13

The bone lesions in renal osteodystrophy are caused by an excess of:

Accepted Answer

A)   ACTH
B)   Thyroglobulin
C)   Parathyroid hormone
D)   Aldosterone
E)   Androgens

Question 14

Rheumatoid arthritis is best classified as:

Accepted Answer

A)   Infectious disease
B)   Degenerative disease
C)   Inborn error of metabolism
D)   Autoimmune disease
E)   Neoplastic disease

Question 15

Which joint disease is characterized by destruction and loss of cartilage,sclerosis of subchondral bone,cyst formation,and osteophytes?

Accepted Answer

A)   Osteoarthritis
B)   Osteomalacia
C)   Rheumatoid arthritis
D)   Gout
E)   Infectious arthritis

Question 16

Benign bone tumor composed of cartilage cells is called:

Accepted Answer

A)   Osteoma
B)   Chondroma
C)   Fibroma
D)   Paget's disease
E)   Ewing's disease

Question 17

Softening of bones as a result of excessive resorption of calcium salts from the extracellular bone matrix is called:

Accepted Answer

A)   Osteoporosis
B)   Osteomalacia
C)   Osteopetrosis
D)   Osteitis deformans
E)   Pellagra

Question 18

Which vitamin is essential for the formation of bones?

Accepted Answer

A)   Vitamin A
B)   Vitamin B₁
C)   Vitamin B₁₂
D)   Vitamin D
E)   Vitamin E

Question 19

Osteomyelitis of long bones is most often caused by:

Accepted Answer

A)   Viruses
B)   Pyogenic bacteria
C)   Mycobacterium tuberculosis
D)   Fungi
E)   Parasites

Question 20

Aseptic necrosis of bones may be caused by all the following except:

Accepted Answer

A)   Sickle cell anemia
B)   Thrombotic occlusion of a nutrient artery
C)   Trauma
D)   Bacteria
E)   Drugs

Exam 19: Bones and Joints