This Nephrectomy Specimen Shows a Lesion in the Kidney of a 63-Year-Old

Multiple Choice

This nephrectomy specimen shows a lesion in the kidney of a 63-year-old man. The lesion is most likely related to

A) a deletion of von Hippel-Lindau (VHL) tumor suppressor gene
B) a mutation of myc oncogene
C) an amplification of ras oncogene
D) a loss of bcl-2 proapoptotic gene
E) an aflatoxin related carcinogen