The Autosomal Dominant Bone Disorder Caused by a Mutation of Fibroblast

Multiple Choice

The autosomal dominant bone disorder caused by a mutation of fibroblast growth factor receptor 3 (FGFR3) is characterized by short stature, rhizomelic shortening of limbs, frontal bossing of the skull, and midface abnormalities. Which of the following disorders is described by these characteristics?

A) Achondrogenesis
B) Achondroplasia
C) Multiple epiphyseal dysplasia
D) Synpolydactyly
E) Holt-Oram syndrome