Which of the Following Mechanisms Does NOT Contribute to the Generation

Multiple Choice

Which of the following mechanisms does NOT contribute to the generation of a cytolytic T lymphocyte (CTL) response to a viral infection?

A) Dendritic cells phagocytose infected cells or viral particles and present them to naive CD8⁺ T cells via the class I MHC pathway.
B) Dendritic cells are infected with the virus and present viral peptides to naive CD8⁺ T cells via the class I MHC pathway.
C) CTLs are directly activated by CD40L expressed on activated helper T cells through CD40.
D) Helper T cells secrete cytokines, such as interleukin-2, that promote the proliferation and differentiation of CD8⁺ T cells.
E) Helper T cells activate infected antigen-presenting cells (APCs) via the CD40 ligand-CD40 pathway, and the activated APCs present viral peptides to naive CD8⁺ T cells via the class I MHC pathway.