Question 1

Which of the following substances are not endogenous?

Accepted Answer

A)  EPO 
B)  testosterone 
C)  Estrogen 
D)  GHB 
E)  none of the above

Question 2

Given the following data:
R/Vd = 0.70L/kg (men) 0.60L/kg (women)
Beta = 0.02 g/dL per hour
Standard drink = 14g
Calculate how many standard drinks a woman (62kg) ingested if her BAC is measured as 0.12g/dL 90 minutes after the BACmax level was reached.

Accepted Answer

A)  2 
B)  3 
C)  4 
D)  6 
E)  none of the above

Question 3

What is physiological pH?

Accepted Answer

A)  6.2 
B)  6.8 
C)  7.4 
D)  8.1 
E)  none of the above

Question 4

One method to detect post-mortem redistribution of a drug is to

Accepted Answer

A)  compare concentrations in the urine to the vitreous fluid 
B)  compare the concentration in the central blood to the peripheral blood 
C)  establish the time of death and test the vitreous fluid 
D)  compare the blood concentration to the liver concentration 
E)  none of the above

Question 5

The physiological reason that a person dies is called the

Accepted Answer

A)  cause of death 
B)  manner of death 
C)  contribution factors to a death 
D)  all of the above 
E)  none of the above

Question 6

The manner of death is classified as

Accepted Answer

A)  purposeful or unintentional 
B)  accidental or purposeful 
C)  accidental, suicide, homicide, or natural 
D)  natural or suspicious 
E)  none of the above

Question 7

Why does ethanol elimination follow zero-order kinetics?

Accepted Answer

A)  the enzymes used become saturated and limit the speed of the reaction 
B)  metabolism occurs outside of the liver 
C)  the enzymes needed are in excess so the ethanol concentration controls the rate of reaction 
D)  ethanol is eliminated through the breath before significant metabolism can occur 
E)  none of the above

Question 8

A weakly basic drug with a pKa of 7.5 partitions from the blood into OF with a pH of 6.7. If ion trapping occurs, where will the drug be trapped?

Accepted Answer

A)  in the blood 
B)  in the oral fluid 
C)  equally in both 
D)  no trapping will occur 
E)  none of the above

Question 9

The units of blood alcohol are typically given in

Accepted Answer

A)  molarity 
B)  g/L 
C)  g/dL 
D)  mg/L 
E)  none of the above

Exam 9: Applications of Forensic Toxicology

Which of the following substances are not endogenous?

Given the following data: R/V_d = 0.70L/kg (men) 0.60L/kg (women) Beta = 0.02 g/dL per hour Standard drink = 14g Calculate how many standard drinks a woman (62kg) ingested if her BAC is measured as 0.12g/dL 90 minutes after the BAC_max level was reached.

What is physiological pH?

One method to detect post-mortem redistribution of a drug is to

The physiological reason that a person dies is called the

The manner of death is classified as

Why does ethanol elimination follow zero-order kinetics?

A weakly basic drug with a pKa of 7.5 partitions from the blood into OF with a pH of 6.7. If ion trapping occurs, where will the drug be trapped?

The units of blood alcohol are typically given in

Exam 9: Applications of Forensic Toxicology

Which of the following substances are not endogenous?

Given the following data: R/Vd = 0.70L/kg (men) 0.60L/kg (women) Beta = 0.02 g/dL per hour Standard drink = 14g Calculate how many standard drinks a woman (62kg) ingested if her BAC is measured as 0.12g/dL 90 minutes after the BACmax level was reached.

What is physiological pH?

One method to detect post-mortem redistribution of a drug is to

The physiological reason that a person dies is called the

The manner of death is classified as

Why does ethanol elimination follow zero-order kinetics?

A weakly basic drug with a pKa of 7.5 partitions from the blood into OF with a pH of 6.7. If ion trapping occurs, where will the drug be trapped?

The units of blood alcohol are typically given in

Given the following data: R/V_d = 0.70L/kg (men) 0.60L/kg (women) Beta = 0.02 g/dL per hour Standard drink = 14g Calculate how many standard drinks a woman (62kg) ingested if her BAC is measured as 0.12g/dL 90 minutes after the BAC_max level was reached.