Question 1

Which compound competes with adenosine for presynaptic autoreceptors, thus preventing adenosine from inhibiting transmitter release.

Accepted Answer

A)  Amphetamine 
B)  Tetrodotoxin 
C)  Botulinum toxin 
D)  Caffeine

Question 2

Explain what it means to say that a drug has a high bioavailability.

Accepted Answer

The answer of Explain what it means to say that...

Question 3

Damage to which site would affect projections using the neurotransmitter norepinephrine?

Accepted Answer

A)  Locus coeruleus 
B)  Raphe nucleus 
C)  Basal forebrain 
D)  Substantia nigra

Question 4

People who have used a particular dose of a drug several times may develop a similar response to the same dosage of other drugs in the same class. This is an example of

Accepted Answer

A)  sensitization. 
B)  tolerance. 
C)  withdrawal. 
D)  cross-tolerance.

Question 5

The mood-stabilizing drug lithium acts by

Accepted Answer

A)  inhibiting cyclic AMP. 
B)  blocking NMDA receptors. 
C)  inhibiting serotonin reuptake. 
D)  activating AMPA receptors.

Question 6

A drug or toxin that resembles the endogenous ligand and that can bind to the receptor and activate it is called as a(n)

Accepted Answer

A)  endogenous drug. 
B)  exogenous mimic. 
C)  receptor agonist. 
D)  receptor antagonist.

Question 7

Curare is a drug that selectively blocks receptors for

Accepted Answer

A)  serotonin. 
B)  GABA. 
C)  acetylcholine. 
D)  norepinephrine.

Question 8

Describe the anatomy of the dopaminergic systems of the brain.

Accepted Answer

The answer of Describe the anatomy of the dopaminergic systems...

Question 9

Most antipsychotic medications act by blocking _______ receptors.

Accepted Answer

The answer of Most antipsychotic medications act by blocking _______...

Question 10

If a newly-developed drug is found to bind to dopamine receptors but does not activate them, the drug is classified as a(n)

Accepted Answer

A)  antagonist. 
B)  endogenous ligand. 
C)  prototype. 
D)  agonist.

Question 11

The _______ model of drug abuse and addiction focuses on the addict's desire to avoid withdrawal symptoms.

Accepted Answer

A)  positive reward 
B)  physical dependence 
C)  disease 
D)  moral

Question 12

One perspective on drug addiction proposes that a feature shared by all habit-forming drugs is that they

Accepted Answer

A)  evoke hallucinations. 
B)  have strong rewarding properties. 
C)  cause a chronic maladaptation syndrome. 
D)  cause bursts of intense activity.

Question 13

Are rodent models of drug addiction useful contributions to substance abuse research? Why or why not? What might be missed with this approach and what findings would you expect to be consistent across species?

Accepted Answer

The answer of Are rodent models of drug addiction useful...

Question 14

Noradrenergic axons project into the

Accepted Answer

A)  limbic system. 
B)  thalamic nuclei. 
C)  cerebral cortex. 
D)  All of the above

Exam 4: The Chemistry of Behavior: Neurotransmitters and Neuropharmacology