Question 1

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Cytoxan 600 mg/m²/wk. Patient height: 70 in , Patient weight: 85 kg What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

a. 85 kg* 2.2 = 187 lb 600 mg/m²/wk * 2.04 m² = 1224 or 1225 mg/wk b. Height 70 in, weight 85 kg, intersects 2.08 m² 600 mg/m²/wk * 2.08 m² = 1248 $\approx$1250 mg/wk

Question 2

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatinum 80 mg/m²/wk. Patient height: 6 ft 2 in , Patient weight: 186 lb What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

a. 80 mg/m²/wk *2.09 m² = 167.2 mg/wk b. Height 74 in, weight 186 lb, intersects 2.10 m² 80 mg/m²/wk *2.10 m² = 168 $\approx$ 170 mg/wk

Question 3

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give mitomycin 15 mg/m²/week. Patient height: 65 in , Patient weight: 64 kg What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

a. 64 kg * 2.2 = 140.8 or 141 lb 15 mg/m²/wk * 1.71 m² = 25.6 or 26 mg/wk b. Height 65 in, weight 64 kg, intersects 1.75 m² 15 mg/m²/wk * 1.75 m² = 26.25 $\approx$ 26 mg/wk

Question 4

Order: clofarabine 52 mg/m² daily and infuse in 250 mL D₅W over 2 hours Patient's height and weight: 5 ft 4 in and 115 lb Drug available: 20 mg/20 mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

Accepted Answer

The answer of Order: clofarabine 52 mg/m² daily and infuse...

Question 5

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give dacarbazine 250 mg/m²/day * 5 days. Patient height: 5 ft 10 in , Patient weight: 173 lb What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 6

Order: sargramostim 250 mcg/m²/day, dilute in 50 mL and infuse over 2 hours Patient's height and weight: 5 ft 10 in and 285 lb Drug available: sargramostim 500 mcg/mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

Accepted Answer

The answer of Order: sargramostim 250 mcg/m²/day, dilute in 50...

Question 7

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give etoposide 120 mg/m²/wk. Patient height: 74 in , Patient weight: 70 kg What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 8

Order: streptozocin 1000 mg/m² in 100 mL D₅W over 2 hours Patient's height and weight: 5 ft 2 in and 210 lb Drug available: streptozocin 1 g powdered vial, reconstitute with 9.5 mL NS; yields 100 mg/mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

Accepted Answer

The answer of Order: streptozocin 1000 mg/m² in 100 mL...

Question 9

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give 5-fluorouracil 450 mg/m²/wk. Patient height: 5 ft 6 in , Patient weight: 210 lb What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 10

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytosine arabinoside 100 mg/m²/day * 7 days. Patient height: 5 ft 2 in , Patient weight: 130 lb What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 11

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Adriamycin 60 mg/m²/wk. Patient height: 70 in , Patient weight: 80 kg What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 12

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytarabine 100 mg/m²/day * 7 days. Patient height: 64 in , Patient weight: 65 kg What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 13

Order: cisplatin 50 mg/m² in 500 mL of NSS intravenously over 90 minutes Patient height and weight: 5 ft 6 in, 160 lb Drug available: cisplatin 100 mg/100 mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

Accepted Answer

The answer of Order: cisplatin 50 mg/m² in 500 mL...

Question 14

Order: cyclophosphamide 500 mg/m² in 500 mL of normal saline solution (NSS) over 90 minutes Patient height and weight: 5 ft 10 in, 142 lb Drug available: cyclophosphamide 100 mg dilute with 5 mL of sterile water; yields 20 mg/mL a. What is the patient's body surface area (BSA) (m²)? b. What is the total dose? c. How many milliliters should you prepare?

Accepted Answer

The answer of Order: cyclophosphamide 500 mg/m² in 500 mL...

Question 15

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give prednisone 60 mg/m²/day * 7 days. Patient height: 72 in , Patient weight: 84 kg What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 16

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give idarubicin hydrochloride 12 mg/m²/day * 3 days. Patient height: 60 in , Patient weight: 60 kg What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 17

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give methotrexate 3.3 mg/m²/day *7 days. Patient height: 72 in , Patient weight: 82 kg What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 18

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give vincristine 2 mg/m²/week. Patient height: 62 in , Patient weight: 75 kg What is the weekly dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Question 19

Order: methotrexate 3 mg/m² PO * 2 weekly Patient's height and weight: 5 ft 2 in and 130 lb Drug available: methotrexate tablets 2.5, 5, 7.5 mg a. What is the patient's BSA (m²)? b. What is the total dose?

Accepted Answer

The answer of Order: methotrexate 3 mg/m² PO * 2...

Question 20

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatin 30 mg/m²/day *3 days. Patient height: 70 in , Patient weight: 80 kg What is the daily dose with a. square root method? b. nomogram?

Accepted Answer

The answer of For the following questions, use the square...

Exam 1: Methods of Calculation for Individualized Drug Dosing

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Cytoxan 600 mg/m2/wk. Patient height: 70 in , Patient weight: 85 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatinum 80 mg/m2/wk. Patient height: 6 ft 2 in , Patient weight: 186 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give mitomycin 15 mg/m2/week. Patient height: 65 in , Patient weight: 64 kg What is the weekly dose with a. square root method? b. nomogram?

Order: clofarabine 52 mg/m2 daily and infuse in 250 mL D5W over 2 hours Patient's height and weight: 5 ft 4 in and 115 lb Drug available: 20 mg/20 mL a. What is the patient's BSA (m2)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give dacarbazine 250 mg/m2/day * 5 days. Patient height: 5 ft 10 in , Patient weight: 173 lb What is the daily dose with a. square root method? b. nomogram?

Order: sargramostim 250 mcg/m2/day, dilute in 50 mL and infuse over 2 hours Patient's height and weight: 5 ft 10 in and 285 lb Drug available: sargramostim 500 mcg/mL a. What is the patient's BSA (m2)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give etoposide 120 mg/m2/wk. Patient height: 74 in , Patient weight: 70 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give 5-fluorouracil 450 mg/m2/wk. Patient height: 5 ft 6 in , Patient weight: 210 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytosine arabinoside 100 mg/m2/day * 7 days. Patient height: 5 ft 2 in , Patient weight: 130 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Adriamycin 60 mg/m2/wk. Patient height: 70 in , Patient weight: 80 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytarabine 100 mg/m2/day * 7 days. Patient height: 64 in , Patient weight: 65 kg What is the daily dose with a. square root method? b. nomogram?

Order: cisplatin 50 mg/m2 in 500 mL of NSS intravenously over 90 minutes Patient height and weight: 5 ft 6 in, 160 lb Drug available: cisplatin 100 mg/100 mL a. What is the patient's BSA (m2)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give prednisone 60 mg/m2/day * 7 days. Patient height: 72 in , Patient weight: 84 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give idarubicin hydrochloride 12 mg/m2/day * 3 days. Patient height: 60 in , Patient weight: 60 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give methotrexate 3.3 mg/m2/day *7 days. Patient height: 72 in , Patient weight: 82 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give vincristine 2 mg/m2/week. Patient height: 62 in , Patient weight: 75 kg What is the weekly dose with a. square root method? b. nomogram?

Order: methotrexate 3 mg/m2 PO * 2 weekly Patient's height and weight: 5 ft 2 in and 130 lb Drug available: methotrexate tablets 2.5, 5, 7.5 mg a. What is the patient's BSA (m2)? b. What is the total dose?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatin 30 mg/m2/day *3 days. Patient height: 70 in , Patient weight: 80 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Cytoxan 600 mg/m²/wk. Patient height: 70 in , Patient weight: 85 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatinum 80 mg/m²/wk. Patient height: 6 ft 2 in , Patient weight: 186 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give mitomycin 15 mg/m²/week. Patient height: 65 in , Patient weight: 64 kg What is the weekly dose with a. square root method? b. nomogram?

Order: clofarabine 52 mg/m² daily and infuse in 250 mL D₅W over 2 hours Patient's height and weight: 5 ft 4 in and 115 lb Drug available: 20 mg/20 mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give dacarbazine 250 mg/m²/day * 5 days. Patient height: 5 ft 10 in , Patient weight: 173 lb What is the daily dose with a. square root method? b. nomogram?

Order: sargramostim 250 mcg/m²/day, dilute in 50 mL and infuse over 2 hours Patient's height and weight: 5 ft 10 in and 285 lb Drug available: sargramostim 500 mcg/mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give etoposide 120 mg/m²/wk. Patient height: 74 in , Patient weight: 70 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give 5-fluorouracil 450 mg/m²/wk. Patient height: 5 ft 6 in , Patient weight: 210 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytosine arabinoside 100 mg/m²/day * 7 days. Patient height: 5 ft 2 in , Patient weight: 130 lb What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give Adriamycin 60 mg/m²/wk. Patient height: 70 in , Patient weight: 80 kg What is the weekly dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cytarabine 100 mg/m²/day * 7 days. Patient height: 64 in , Patient weight: 65 kg What is the daily dose with a. square root method? b. nomogram?

Order: cisplatin 50 mg/m² in 500 mL of NSS intravenously over 90 minutes Patient height and weight: 5 ft 6 in, 160 lb Drug available: cisplatin 100 mg/100 mL a. What is the patient's BSA (m²)? b. What is the total dose? c. How many milliliters should you prepare?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give prednisone 60 mg/m²/day * 7 days. Patient height: 72 in , Patient weight: 84 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give idarubicin hydrochloride 12 mg/m²/day * 3 days. Patient height: 60 in , Patient weight: 60 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give methotrexate 3.3 mg/m²/day *7 days. Patient height: 72 in , Patient weight: 82 kg What is the daily dose with a. square root method? b. nomogram?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give vincristine 2 mg/m²/week. Patient height: 62 in , Patient weight: 75 kg What is the weekly dose with a. square root method? b. nomogram?

Order: methotrexate 3 mg/m² PO * 2 weekly Patient's height and weight: 5 ft 2 in and 130 lb Drug available: methotrexate tablets 2.5, 5, 7.5 mg a. What is the patient's BSA (m²)? b. What is the total dose?

For the following questions, use the square root method and/or nomogram. Note discrepancies between methods. Give cisplatin 30 mg/m²/day *3 days. Patient height: 70 in , Patient weight: 80 kg What is the daily dose with a. square root method? b. nomogram?