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Blood Samples for Therapeutic Drug Monitoring That Are Collected in Evacuated

Question 17

Multiple Choice

Blood samples for therapeutic drug monitoring that are collected in evacuated tubes with stoppers containing tris-(2-butoxyethyl) phosphate (TBEP) as the plasticizer are subject to which of the following?


A) falsely decreased serum concentrations of monitored drugs due to the plasticizer's ability to displace drugs from transport proteins
B) falsely increased serum concentrations of monitored drugs due to the plasticizer's ability to displace drugs from transport proteins
C) falsely decreased serum concentrations of monitored drugs due to the dilutional effect of plasticizer being released into the blood sample
D) falsely increased serum concentrations of monitored drugs because the plasticizer is measured as part of the drug concentration

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