Question 1

In which of the following organs would you expect to find adhesive junctions in humans?

Accepted Answer

A)  heart muscle
B)  skin epithelium
C)  uterus
D)  both choices A and B
E)  choices A, B, and C E

Question 2

A person is genotypically blood type A.However,this individual also does not produce the lipid to which N-acetylgalactosamine is added,so the lipid is therefore not expressed on the surface of erythrocytes.This situation is known as the Bombay phenotype.When tested,this person will appear to be blood type

Accepted Answer

A)  A.
B)  B.
C)  AB.
D)  O. D

Question 3

Which of the following statements is true regarding cell-cell adhesion?

Accepted Answer

A)  Adhesion is coordinated with many cellular processes except cell survival.
B)  Adhesion molecules include plakoglobulin, which cements two cells together.
C)  Adherens junctions are exclusive to plant cells.
D)  Adhesive junctions are characterized by the attachment of long molecules of hyaluronate.
E)  Adhesive junctions are dynamic in response to cellular signals. E

Question 4

You discover a dog suffering from a strange disorder that is due to an autoimmune response against its own cells.Upon further investigation,you find that the cells of various tissues are loosely arranged and do not have characteristic shapes and that the animal is prone to hemorrhage as the result of poor blood clotting.Based on these results,the target of the autoimmune response could be

Accepted Answer

A)  fibronectins.
B)  laminins.
C)  extensins.
D)  pectins.
E)  desmotubules.

Question 5

Which of the following activities is not associated with cadherins?

Accepted Answer

A)  segregation of cells to specific tissues
B)  paracellular transport
C)  embryonic development
D)  establishment of synaptic connections
E)  loss of activity associated with cancer

Question 6

An elderly patient presents with blistering of the skin.You suspect an autoimmune disorder.If your suspicions are correct,the patient's serum should contain antibodies reactive to

Accepted Answer

A)  talin.
B)  vinculin.
C)  α-actinin.
D)  BPAG.
E)  actin.

Question 7

Which of the following is correctly paired with regard to similarity in function?

Accepted Answer

A)  adhesive junctions-tight junctions
B)  desmotubule-gap junction
C)  tight junctions-gap junctions
D)  plaques-plasmodesmata
E)  connexons-desmosomes

Question 8

Which of the following is not associated with the basal lamina?

Accepted Answer

A)  serves as a structural support
B)  allows for movement of some small molecules
C)  can influence cell migrations in certain areas of the body
D)  contains collagen type IV, proteoglycans, laminins, and entactin
E)  contains the most abundant supply of fibronectins.

Question 9

________ are insoluble polymers of aromatic alcohols that are primarily found in woody tissues.

Accepted Answer

The answer of ________ are insoluble polymers of aromatic alcohols...

Question 10

Of the proteoglycans associated with the extracellular matrix in vertebrates,which of the following is associated with the lubrication of joints?

Accepted Answer

A)  chondroitin sulfate
B)  glucuronate
C)  hyaluronate
D)  keratan sulfate
E)  mucoproteins

Question 11

In the extracellular matrix of animal cells,collagen and elastin fibers are embedded with this matrix.

Accepted Answer

A)  glycoaminoglycans
B)  proteoglycans
C)  pectins
D)  lignins
E)  both choices A and B

Question 12

The organ where you would most likely expect to find actin microfilaments continuous with adherens junctions is the

Accepted Answer

A)  liver.
B)  stomach.
C)  kidney.
D)  brain.
E)  heart.

Question 13

A type of adhesive junction that is associated with the connection between an epithelial cell and the basal lamella is the

Accepted Answer

A)  hemidesmosome.
B)  desmosome.
C)  gap junction.
D)  plasmodesmata.
E)  focal contact.

Question 14

You are investigating a clinical disorder in one of your patients.You discover that the patient has an autoimmune disease that targets and destroys fibroblasts.This disorder would most likely affect

Accepted Answer

A)  fiber production by the cells, as occurs with blood clotting.
B)  annulus formation.
C)  hyluronate production in the joints.
D)  collagen production.
E)  all of the above

Question 15

The protein invasin is associated with

Accepted Answer

A)  Yersinia psuedotuberculosis.
B)  the construction of an integrin network in bacteria.
C)  plasmodemata.
D)  tight-junction ridge formation.
E)  lubrication of joints.

Question 16

The function of integrin-linked kinase during integrin-based signaling is

Accepted Answer

A)  integrin activation.
B)  anchorage-dependent growth.
C)  scaffolding protein.
D)  cell movement.
E)  anchorage-independent growth.

Question 17

A newly defined autoimmune disorder has resulted in an immune response against Type V collagen fibers.As a result,the most likely organ to be targeted in this response would be the

Accepted Answer

A)  skin.
B)  heart.
C)  lungs.
D)  stomach.
E)  tongue.

Question 18

The primary polysaccharides associated with the plant cell wall are the

Accepted Answer

A)  hemicelluloses.
B)  extensins.
C)  fibronectins.
D)  pectins.
E)  both choices A and D

Question 19

Which of the following is not associated with adhesive junctions?

Accepted Answer

A)  desmosomes
B)  hemidesmosomes
C)  plaques
D)  connexin
E)  cadherins

Question 20

In animal cells,the extracellular matrix plays important roles in all of the following processes except

Accepted Answer

A)  cell division.
B)  motility.
C)  DNA replication.
D)  differentiation.
E)  adhesion.

Exam 17: Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures