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The Following Southern Blot Was Performed to Examine a Mutation

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The following Southern blot was performed to examine a mutation that is linked to a genetic disease.The blot was probed with fluorescent-labeled cDNA of the gene.What is the most likely explanation for the abnormal bands in the patient in comparison with the normal control? The following Southern blot was performed to examine a mutation that is linked to a genetic disease.The blot was probed with fluorescent-labeled cDNA of the gene.What is the most likely explanation for the abnormal bands in the patient in comparison with the normal control?   A) Faulty splicing of the messenger RNA (mRNA) . B) The deletion of an entire exon. C) A single-nucleotide polymorphism. D) Duplication of at least one exon. E) The expansion of a microsatellite.


A) Faulty splicing of the messenger RNA (mRNA) .
B) The deletion of an entire exon.
C) A single-nucleotide polymorphism.
D) Duplication of at least one exon.
E) The expansion of a microsatellite.

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