In Most Individuals with Inherited Colon Cancer Susceptibility Who Do

Multiple Choice

In most individuals with inherited colon cancer susceptibility who do not have excessive numbers of benign and premalignant polyps, the cancer susceptibility is caused by a heterozygous defect in a gene for:

A) Postreplication mismatch repair.
B) Genome-wide nucleotide excision repair.
C) The lipid phosphatase PTEN.
D) The antiapoptotic protein Bcl2.
E) The transcriptional regulator p53.