What Effect Would a Loss of Shh Expression Within the Urethral

Multiple Choice

What effect would a loss of Shh expression within the urethral plate have on genital development?

A) Development of enlarged genital tubercle
B) Hypospadia
C) An increase in Hoxa13 and Hoxd3 expression in the genital tubercle
D) An increase in Fgf8 expression in the urethral plate